Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 3/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20408305 | 0.90 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1LMNASIGMAR1 | |
| SCHEMBL5590707 | 0.84 | GABRA1 (0.40) | GABRA1GABRB2LMNASIGMAR1 | |
| SCHEMBL15944591 | 0.82 | GABRA1 (0.41) | GABRA1GABRB2LMNASIGMAR1 | |
| SCHEMBL3736881 | 0.78 | DAO (0.34) | GABRA1GABRB2DAO | |
| SCHEMBL14373124 | 0.77 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1LMNASIGMAR1 | |
| SCHEMBL16141705 | 0.77 | GABRA1 (0.55) | GABRA1GABRB2ELANE | |
| SCHEMBL14280822 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1LMNASIGMAR1 | |
| SCHEMBL4883849 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1LMNACACNA1C | |
| SCHEMBL3736278 | 0.77 | DAO (0.33) | GABRA1GABRB2DAO | |
| SCHEMBL4883854 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1LMNACACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617360-B2 | Process for the preparation of (co) polymers of conjugated dienes in the presence of a catalytic system comprising a bis-imine complex of cobalt | VERSALIS S.P.A. (IT) | 2017-04-11 | — | — | US | disclosed |
| US-9617360-B2 | Process for the preparation of (co) polymers of conjugated dienes in the presence of a catalytic system comprising a bis-imine complex of cobalt | VERSALIS S.P.A. (IT) | 2017-04-11 | — | — | US | disclosed |
| EP-2935361-B1 | PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINE COMPLEX OF COBALT | VERSALIS SPA (IT) | 2016-12-07 | — | — | EP | disclosed |
| US-9512252-B2 | Bis-imine complex of lanthanides, catalytic system comprising said bis-imine complex and process for the (co)polymerization of conjugated dienes | VERSALIS S.P.A. (IT) | 2016-12-06 | — | — | US | disclosed |
| US-9512252-B2 | Bis-imine complex of lanthanides, catalytic system comprising said bis-imine complex and process for the (co)polymerization of conjugated dienes | VERSALIS S.P.A. (IT) | 2016-12-06 | — | — | US | disclosed |
| US-20150329651-A1 | PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINE COMPLEX OF COBALT | VERSALIS S.P.A. (IT) | 2015-11-19 | — | — | US | disclosed |
| US-20150329651-A1 | PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINE COMPLEX OF COBALT | VERSALIS S.P.A. (IT) | 2015-11-19 | — | — | US | disclosed |
| US-20140228206-A1 | BIS-IMINE COMPLEX OF LANTHANIDES, CATALYTIC SYSTEM COMPRISING SAID BIS-IMINE COMPLEX AND PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES | VERSALIS S.P.A. (IT) | 2014-08-14 | — | — | US | disclosed |
| US-20140228206-A1 | BIS-IMINE COMPLEX OF LANTHANIDES, CATALYTIC SYSTEM COMPRISING SAID BIS-IMINE COMPLEX AND PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES | VERSALIS S.P.A. (IT) | 2014-08-14 | — | — | US | disclosed |
| WO-2014097199-A1 | PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINE COMPLEX OF COBALT | VERSALIS S.P.A. (IT) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013037910-A1 | BIS-IMINE COMPLEX OF LANTHANIDES, CATALYTIC SYSTEM COMPRISING SAID BIS-IMINE COMPLEX AND PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES | VERSALIS S.P.A. (IT) | 2013-03-21 | — | — | WO | disclosed |
| US-7998895-B2 | Catalysts for olefin polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-16 | — | — | US | disclosed |
| US-7998895-B2 | Catalysts for olefin polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-16 | — | — | US | disclosed |
| US-20100222531-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222531-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-04 | — | — | US | disclosed |
| US-7439314-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439314-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222531-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | PORCN, PUF60, CAD | GABRA1 4120/4885GABRB2 4045/4885ALDH1A1 3187/4885 |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | PORCN, PUF60, CAD | GABRA1 4120/4885GABRB2 4045/4885ALDH1A1 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.