SCHEMBL12384045

SCHEMBL12384045

CC(CC(C)(C)c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 2/20 0.43
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10794218 0.82 TSHR (0.43)
SCHEMBL3151324 0.81 MAPT (0.49) PDE2A
SCHEMBL3480352 0.81 SHBG (0.52)
SCHEMBL19012408 0.79 ALDH1A1 (0.44) CA1CA2
SCHEMBL435755 0.78 PDE2A (0.52) PDE2ACA1CA2
SCHEMBL13622230 0.78 PDE2A (0.52) PDE2ACA1CA2
SCHEMBL28347282 0.78 PDE2A (0.52) PDE2ACA1CA2
SCHEMBL27760120 0.78 EEF2K (0.44)
SCHEMBL21671652 0.77 NPC1 (0.49)
SCHEMBL792982 0.76 TAAR1 (0.54) PDE2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476621-B2 Resin composition, gate insulating layer, and organic thin film transistor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-02 US disclosed
US-20110193071-A1 RESIN COMPOSITION, GATE INSULATING LAYER, AND ORGANIC THIN FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-11 US disclosed