SCHEMBL12387537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13888818	0.93	—	—
	SCHEMBL12387541	0.93	ESR1 (0.37)	BACE1ESR1ESR2KDM4EALDH1A1
	SCHEMBL13888816	0.93	—	—
	SCHEMBL12387548	0.92	ALDH1A1 (0.37)	KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL13888823	0.92	—	—
	SCHEMBL13888825	0.90	KDM4E (0.30)	KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL13888817	0.90	KDM4E (0.30)	KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL15316847	0.90	ESR1 (0.35)	BACE1ESR1ESR2KDM4EALDH1A1
	SCHEMBL13888824	0.89	CHRNA1 (0.31)	—
	SCHEMBL12387540	0.88	CA12 (0.38)	KDM4EALDH1A1CYP1A2MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.