Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694950 | 0.80 | RAB9A (0.73) | LMNAKMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2915189 | 0.79 | LMNA (0.54) | LMNAKMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28248353 | 0.79 | KMT2A (0.80) | LMNAKMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12394335 | 0.79 | KMT2A (0.62) | LMNAKMT2ASMN1; SMN2ALDH1A1TRPV1 | |
| SCHEMBL14345137 | 0.77 | PKM (0.58) | LMNAKMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5209151 | 0.77 | RAB9A (0.64) | LMNAKMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL17731943 | 0.77 | LMNA (1.00) | LMNAKMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22501883 | 0.77 | POLB (0.74) | LMNAKMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL17270179 | 0.76 | ACKR3 (0.74) | LMNAKMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12394254 | 0.76 | PKM (0.62) | LMNAKMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008303-B2 | e.g. 6-Methyl-biphenyl-3,4'-dicarboxylic acid 4'-[(3-bromo-phenyl)-amide]-[(4 morpholin-4-yl-phenyl)-amide]; viricide; with other active viricide such as interferon or ribavirin | ASTRAZENECA AB (SE) | 2011-08-30 | — | — | US | disclosed |