Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.44 |
| ▸ | LYPLA1 | O75608 | 5/20 | 0.43 |
| ▸ | LYPLA2 | O95372 | 5/20 | 0.43 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16551913 | 0.90 | PLA2G6 (0.54) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL12370966 | 0.88 | LYPLA1 (0.52) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL16194493 | 0.85 | PLA2G6 (0.62) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL16194492 | 0.85 | PLA2G6 (0.62) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL12370960 | 0.83 | PLA2G6 (0.60) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL16201802 | 0.83 | PLA2G6 (0.60) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL16201817 | 0.83 | PLA2G6 (0.56) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL15012623 | 0.81 | PLA2G6 (0.51) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL16201811 | 0.81 | PLA2G6 (0.51) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A | |
| SCHEMBL15012624 | 0.81 | PLA2G6 (0.51) | DAGLALYPLA1LYPLA2PLA2G6PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9521845-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITÄT-MÜNCHEN (DE) | 2016-12-20 | — | — | US | disclosed |
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-06-12 | — | — | US | disclosed |
| US-8669283-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-03-11 | — | — | US | disclosed |
| US-8563598-B2 | — | — | 2013-10-22 | — | — | US | disclosed |
| US-20110196027-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | DAGLA 219/4885LYPLA1 651/4885LYPLA2 1208/4885 |
| US-20110196027-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | DAGLA 219/4885LYPLA1 651/4885LYPLA2 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.