Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232214 | 0.88 | CYP3A4 (0.45) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL11231068 | 0.88 | CYP3A4 (0.45) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL59852 | 0.81 | CYP3A4 (0.48) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL109084 | 0.81 | CYP3A4 (0.48) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| Benzene SCHEMBL28982643 | 0.77 | CYP3A4 (0.45) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL7002811 | 0.75 | CYP3A4 (0.44) | CYP3A4TSHRTRPA1CYP1A2MAPK1 | |
| SCHEMBL22572895 | 0.75 | CYP3A4 (0.35) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL11097683 | 0.74 | CYP3A4 (0.71) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL58461 | 0.73 | GABRA1 (0.50) | CYP3A4TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL22080193 | 0.73 | CYP3A4 (0.44) | CYP3A4TSHRTRPA1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946133-B2 | Method and composition for curing lost circulation | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20110183871-A1 | Method and composition for curing lost circulation | SCHLUMBERGER TECHNOLOGY CORPORATION | 2011-07-28 | — | — | US | disclosed |