Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16606313 | 0.86 | HDAC3 (0.47) | CHRM2KDM4EALDH1A1VNN1CYP1A2 | |
| SCHEMBL230222 | 0.86 | CHRM2 (0.70) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL29438821 | 0.86 | CHRM2 (0.70) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL317984 | 0.84 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| Zinc Ion SCHEMBL30442739 | 0.84 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL25211342 | 0.84 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL18493706 | 0.84 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| Zinc Ion SCHEMBL30205248 | 0.84 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL28117672 | 0.84 | ALDH1A1 (0.57) | ALDH1A1VNN1CYP1A2CYP2D6MEN1 | |
| Pyridine SCHEMBL4753513 | 0.82 | CHRM2 (0.61) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574914-B2 | Methods for mobile zinc measurement | THE GENERAL HOSPITAL CORPORATION (US) | 2013-11-05 | — | — | US | claimed |
| US-20120270262-A1 | METHODS FOR MOBILE ZINC MEASUREMENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-25 | — | — | US | claimed |
| WO-2011019864-A2 | METHODS FOR MOBILE ZINC MEASUREMENT | THE GENERAL HOSPITAL CORPORATION (US) | 2011-02-17 | — | — | WO | claimed |
| EP-2393805-B1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM INC (US) | 2015-08-26 | — | — | EP | disclosed |
| US-9006437-B2 | Xanthene dyes comprising a sulfonamide group | BIOTIUM, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150004711-A1 | METHODS AND ASSAYS RELATING TO PROSTATE CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2015-01-01 | — | — | US | disclosed |
| US-20140011208-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. | 2014-01-09 | — | — | US | disclosed |
| US-8574914-B2 | Methods for mobile zinc measurement | THE GENERAL HOSPITAL CORPORATION (US) | 2013-11-05 | — | — | US | disclosed |
| WO-2013126501-A1 | METHODS AND ASSAYS RELATING TO PROSTATE CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |
| US-20120270262-A1 | METHODS FOR MOBILE ZINC MEASUREMENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-25 | — | — | US | disclosed |
| EP-2393805-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | Biotium Inc. (US) | 2011-12-14 | — | — | EP | disclosed |
| WO-2011019864-A2 | METHODS FOR MOBILE ZINC MEASUREMENT | THE GENERAL HOSPITAL CORPORATION (US) | 2011-02-17 | — | — | WO | disclosed |
| WO-2010091126-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. (US) | 2010-08-12 | — | — | WO | disclosed |