Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397408 | 0.91 | APP (0.32) | ESR1ESR2APPCYP1A1CYP1A2 | |
| SCHEMBL10045627 | 0.77 | ALDH1A1 (0.37) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL12397401 | 0.76 | CA2 (0.36) | CA2 | |
| SCHEMBL12278472 | 0.73 | APP (0.42) | ESR1ESR2APPERN1HSD17B1 | |
| SCHEMBL25061111 | 0.72 | APP (0.40) | ESR1ESR2APPERN1HSD17B1 | |
| SCHEMBL25061055 | 0.72 | APP (0.40) | ESR1ESR2APPERN1HSD17B1 | |
| SCHEMBL18843167 | 0.72 | ESR1 (0.40) | ESR1ESR2APPERN1HSD17B1 | |
| SCHEMBL9976850 | 0.72 | APP (0.50) | ESR1ESR2APPERN1HSD17B1 | |
| SCHEMBL12277767 | 0.72 | APP (0.41) | ESR1ESR2APPERN1HSD17B1 | |
| SCHEMBL15025856 | 0.71 | ADORA2A (0.34) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985353-B2 | Semiconductors; electronics; organic field effect transistors | MERCK PATENT GMBH (DE) | 2011-07-26 | — | — | US | disclosed |
| US-20080197325-A1 | Oligomeric Polyacene and Semiconductor Formulations | MERCK PATENT GMBH (DE) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080197325-A1 | Oligomeric Polyacene and Semiconductor Formulations | OR51E2, OR10J3, OSTC | ESR1 459/4885ESR2 2744/4885APP 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.