Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842254 | 0.92 | ALDH1A1 (0.51) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12239935 | 0.90 | ALDH1A1 (0.49) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12239944 | 0.90 | HTT (0.49) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12397453 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL1357175 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL1357442 | 0.89 | HTT (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12239945 | 0.83 | HTT (0.51) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12239928 | 0.82 | LMNA (0.44) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL29062620 | 0.82 | HTT (0.70) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12239938 | 0.82 | HTT (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580967-B2 | Methyl 3-(benzyloxy)-1-(2,2-dihydroxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate and processes for the preparation thereof | SHIONOGI & CO., LTD. (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20110183940-A1 | CHEMICAL COMPOUNDS | VIIV HEALTHCARE COMPANY | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183940-A1 | CHEMICAL COMPOUNDS | PAICS, APRT, SAMHD1 | ALDH1A1 1616/4885HTT 3836/4885HPGD 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.