Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.45 |
| ▸ | PGR | P06401 | 8/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.45 |
| ▸ | AR | P10275 | 8/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397686 | 0.94 | NR3C1 (0.47) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL2161713 | 0.88 | NR3C1 (0.44) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL12397695 | 0.88 | NR3C1 (0.41) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL12397541 | 0.85 | NR3C1 (0.43) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL12397692 | 0.85 | NR3C1 (0.42) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL12397545 | 0.83 | NR3C1 (0.44) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL1423391 | 0.82 | NR3C1 (0.46) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL12397653 | 0.81 | MGAM (0.43) | NR3C1MGAMGAASIMGAM2 | |
| SCHEMBL12397636 | 0.81 | GAA (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL12397777 | 0.81 | NR3C1 (0.47) | NR3C1PGRNR3C2ARPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183928-A1 | 3-Cyanoalkyl- and 3-hydroxyalkylindoles and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183928-A1 | 3-Cyanoalkyl- and 3-hydroxyalkylindoles and use thereof | HTR3C, HTR3A, ADRB3 | NR3C1 2099/4885PGR 4721/4885NR3C2 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.