Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.71 |
| ▸ | MAPT | P10636 | 9/20 | 0.71 |
| ▸ | LMNA | P02545 | 7/20 | 0.64 |
| ▸ | HTT | P42858 | 7/20 | 0.64 |
| ▸ | TP53 | P04637 | 5/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976178 | 0.89 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL2966537 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL31642640 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL17511740 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL21482708 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL1980247 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL28102527 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL16218976 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL8177086 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL12443641 | 0.82 | MAPT (0.69) | ALDH1A1MAPTLMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423433-B1 | SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES | BIO PHARM SOLUTIONS CO LTD (KR) | 2025-12-17 | — | — | EP | disclosed |
| CN-112811994-B | Difluoro ether compound with 3-pentenyl end group and synthesis method thereof | 江苏和成新材料有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-109071424-B | Sulfamate derivative compound, preparation method and application thereof | 生物药品解决方案有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-112811994-A | Difluoro ether compound with end group of 3-pentenyl and synthesis method thereof | 江苏和成新材料有限公司 | 2021-05-18 | — | — | CN | disclosed |
| US-20210115044-A1 | TRICYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-04-22 | — | — | US | disclosed |
| EP-3784241-A1 | TRICYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | Merck Sharp&Dohme Corp. (US) | 2021-03-03 | — | — | EP | disclosed |
| CN-112088005-A | Tricyclic heterocyclic compounds useful as HIV integrase inhibitors | 默沙东公司 | 2020-12-15 | — | — | CN | disclosed |
| US-10351519-B2 | Sulfamate derivative compounds, processes for preparing them and their uses | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2019-07-16 | — | — | US | disclosed |
| US-10351519-B2 | Sulfamate derivative compounds, processes for preparing them and their uses | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2019-07-16 | — | — | US | disclosed |
| EP-3423433-A1 | SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES | Bio-Pharm Solutions Co., Ltd. (KR) | 2019-01-09 | — | — | EP | disclosed |
| EP-1521752-B1 | MACROCYCLES FOR THE TREATMENT OF CANCER | BIOTECHNOLOG FORSCHUNG GMBH (DE) | 2009-02-25 | — | — | EP | disclosed |
| EP-1521752-B1 | MACROCYCLES FOR THE TREATMENT OF CANCER | BIOTECHNOLOG FORSCHUNG GMBH (DE) | 2009-02-25 | — | — | EP | disclosed |
| CN-101203483-A | N-substituted phenylacetamide derivatives and pharmaceutical compositions containing the same | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-06-18 | — | — | CN | disclosed |
| EP-1884510-A1 | N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-02-06 | — | — | EP | disclosed |
| US-20060128966-A1 | Thia-epothilone derivatives for the treatment of cancer | MORPHONCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2006-06-15 | — | — | US | disclosed |
| US-20060004065-A1 | Novel macrocycles for the treatment of cancer | WOLFGANG RICHTER (DE) | 2006-01-05 | — | — | US | disclosed |
| EP-1567524-A1 | THIA-EPOTHILONE DERIVATIVES FOR THE TREATMENT OF CANCER | Richter, Wolfgang (DE) | 2005-08-31 | — | — | EP | disclosed |
| EP-1521752-A1 | NOVEL MACROCYCLES FOR THE TREATMENT OF CANCER | Gesellschaft fur Biotechnologische Forschung mbH (gbf) (DE) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004048372-A1 | THIA-EPOTHILONE DERIVATIVES FOR THE TREATMENT OF CANCER | MORPHOCHEM AG KOMB CHEMIE (DE) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004007492-A1 | NOVEL MACROCYCLES FOR THE TREATMENT OF CANCER | GESELLSCHAFT FUER BIOTECHNOLGISCHE FORSCHUNG MBH (GBF) (DE) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128966-A1 | Thia-epothilone derivatives for the treatment of cancer | TTPA, THPO, TERT | ALDH1A1 190/4885MAPT 4190/4885LMNA 3897/4885 |
| US-20210115044-A1 | TRICYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | TYMP, CCNI, TYMS | ALDH1A1 706/4885MAPT 3652/4885LMNA 2148/4885 |
| US-20060004065-A1 | Novel macrocycles for the treatment of cancer | CCNI, CCNB1, CCNC | ALDH1A1 1428/4885MAPT 4152/4885LMNA 2796/4885 |
| US-10351519-B2 | Sulfamate derivative compounds, processes for preparing them and their uses | STS, SULT2A1, SULT1A1 | ALDH1A1 844/4885MAPT 379/4885LMNA 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.