Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163256 | 0.82 | GAA (1.00) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL29449723 | 0.79 | NOTUM (1.00) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL11981335 | 0.79 | NOTUM (0.68) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL396037 | 0.79 | NOTUM (1.00) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL160329 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL23409642 | 0.75 | TSHR (0.71) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2165230 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL29804966 | 0.75 | NOTUM (0.72) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL5492978 | 0.75 | SMN1; SMN2 (0.79) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL17117378 | 0.75 | NOTUM (0.72) | ALDH1A1MAPTLMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985763-B2 | using an thiourea compound or carbonyl thiourea compound; therapy for drug resistant infections | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-07-26 | — | — | US | disclosed |