Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2274086 | 0.81 | RAB9A (0.39) | ALDH1A1LMNASMN1; SMN2RAB9AMAPT | |
| SCHEMBL21091281 | 0.80 | NSD1 (0.58) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 | |
| SCHEMBL474219 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 | |
| SCHEMBL2314657 | 0.74 | NSD1 (0.64) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 | |
| SCHEMBL14044812 | 0.74 | HSD17B10 (0.68) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 | |
| SCHEMBL2273350 | 0.73 | MEN1 (0.42) | ALDH1A1LMNASMN1; SMN2RAB9AMAPT | |
| SCHEMBL23196210 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 | |
| SCHEMBL21396110 | 0.72 | HSD17B10 (0.38) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 | |
| SCHEMBL19627252 | 0.71 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 | |
| SCHEMBL20633445 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2HSD17B10NSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994337-B2 | Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090118272-A1 | BENZOTHIAZOLE AND AZABENZOTHIAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2009-05-07 | — | — | US | disclosed |
| US-7473784-B2 | Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118272-A1 | BENZOTHIAZOLE AND AZABENZOTHIAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | GRK2, MAPK9, MAPK1 | ALDH1A1 2753/4885LMNA 3666/4885SMN1; SMN2 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.