Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | CCR1 | P32246 | 3/20 | 0.69 |
| ▸ | CCR5 | P51681 | 3/20 | 0.69 |
| ▸ | CCR8 | P51685 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | ALPL | P05186 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | ALPI | P09923 | 1/20 | 0.69 |
| ▸ | ALPG | P10696 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993751 | 0.90 | KDM4E (0.78) | KDM4ETP53CCR1CCR5CCR8 | |
| SCHEMBL12402912 | 0.86 | KDM4E (0.59) | KDM4ETP53CCR1CCR5CCR8 | |
| Terpyridine SCHEMBL57442 | 0.83 | KDM4E (1.00) | KDM4ETP53CCR1CCR5CCR8 | |
| SCHEMBL30172832 | 0.83 | KDM4E (1.00) | KDM4ETP53CCR1CCR5CCR8 | |
| SCHEMBL7964803 | 0.83 | KDM4E (1.00) | KDM4ETP53CCR1CCR5CCR8 | |
| Terpyridine SCHEMBL29357603 | 0.83 | KDM4E (1.00) | KDM4ETP53CCR1CCR5CCR8 | |
| SCHEMBL9611814 | 0.82 | KDM4E (0.60) | KDM4ETP53CCR1CCR5CCR8 | |
| SCHEMBL12999304 | 0.81 | KDM4E (0.64) | KDM4ETP53CCR1CCR5CCR8 | |
| SCHEMBL12999271 | 0.81 | KDM4E (0.64) | KDM4ETP53CCR1CCR5CCR8 | |
| Terpyridine SCHEMBL1616654 | 0.81 | KDM4E (0.95) | KDM4ETP53CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867623-B1 | TERPHENYLENE DERIVATIVES, TETRAHALOTERPHENYL DERIVATIVES AND PROCESSES FOR THE PRODUCTION OF BOTH | TOSOH CORP (JP) | 2017-05-10 | — | — | EP | disclosed |
| US-7985885-B2 | Terphenylene derivative, tetrahaloterphenyl derivative, and processes for producing both | TOSOH CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-7985885-B2 | Terphenylene derivative, tetrahaloterphenyl derivative, and processes for producing both | TOSOH CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20090023957-A1 | TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH | TOSOH CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| US-20090023957-A1 | TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH | TOSOH CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1867623-A1 | TERPHENYLENE DERIVATIVES, TETRAHALOTERPHENYL DERIVATIVES AND PROCESSES FOR THE PRODUCTION OF BOTH | Tosoh Corporation (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023957-A1 | TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH | TERT, TLN1, TTI1 | KDM4E 353/4885TP53 3718/4885CCR1 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.