SCHEMBL1240367

SCHEMBL1240367

C=CC(C=C)COc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
SCN4A P35499 2/20 0.48
MAOA P21397 1/20 0.46
PTGS1 P23219 1/20 0.46
KCNA3 P22001 1/20 0.44
THRB P10828 1/20 0.42
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
CYP2D6 P10635 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RECQL P46063 1/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
MTOR P42345 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5512795 0.79 LMNA (0.47) LMNASCN4AMAOAPTGS1KCNA3
SCHEMBL24726827 0.79 LMNA (0.57) LMNASCN4AMAOAPTGS1THRB
SCHEMBL13392791 0.79 LMNA (0.57) LMNASCN4AMAOAPTGS1THRB
SCHEMBL1239744 0.78 KCNA3 (0.56) KCNA3THRBTAAR1ALDH1A1RECQL
SCHEMBL9681057 0.76 LMNA (0.57) LMNASCN4AMAOAPTGS1KCNA3
SCHEMBL11795671 0.75 LMNA (0.47) LMNASCN4AMAOAPTGS1KCNA3
SCHEMBL1239723 0.75 KCNA3 (0.57) KCNA3THRBTAAR1ALDH1A1RECQL
SCHEMBL10998858 0.72 LMNA (0.49) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL23239453 0.72 LMNA (0.53) LMNASCN4AMAOAPTGS1KCNA3
SCHEMBL1811045 0.72 LMNA (0.53) LMNACYP2D6L3MBTL1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7892694-B2 Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same KABUSHIKI KAISHA TOSHIBA (JP) 2011-02-22 US disclosed
US-20070166590-A1 ELECTROLYTIC MEMBRANE, PROCESS FOR PRODUCING THE SAME, MEMBRANE ELECTRODE ASSEMBLY, FUEL CELL AND METHOD OF OPERATING THE SAME KABUSHIKI KAISHA TOSHIBA (JP) 2007-07-19 US disclosed