SCHEMBL5512795

SCHEMBL5512795

C=CC(COc1ccccc1)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
SCN4A P35499 2/20 0.46
MAOA P21397 1/20 0.43
PTGS1 P23219 1/20 0.43
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
KCNA3 P22001 1/20 0.41
THRB P10828 1/20 0.40
MTNR1A P48039 3/20 0.39
MTNR1B P49286 3/20 0.39
CYP2D6 P10635 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
KDM4E B2RXH2 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
NPC1 O15118 1/20 0.38
MTOR P42345 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9327516 0.80 ALDH1A1 (0.38) LMNAPPARGPPARAKCNA3THRB
SCHEMBL9146066 0.80 MEN1 (0.44) LMNAPPARGPPARAMTNR1AMTNR1B
SCHEMBL11144146 0.80 POLB (0.33) LMNAPPARGPPARAKCNA3THRB
SCHEMBL7600323 0.80 CYP2C19 (0.39) KCNA3THRBMTNR1AMTNR1BL3MBTL1
SCHEMBL1240367 0.79 LMNA (0.50) LMNASCN4AMAOAPTGS1KCNA3
SCHEMBL5523158 0.78 ALDH1A1 (0.42) LMNAPPARGPPARATHRBMTNR1A
SCHEMBL24726827 0.76 LMNA (0.57) LMNASCN4AMAOAPTGS1THRB
SCHEMBL13392791 0.76 LMNA (0.57) LMNASCN4AMAOAPTGS1THRB
SCHEMBL5516567 0.75 LMNA (0.51) LMNATHRBMTNR1AMTNR1BCYP2D6
SCHEMBL294015 0.75 LMNA (0.50) LMNASCN4AMAOAPTGS1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4182901-A AND SUITABLE CARBOXYLIC ACID PHILLIPS PETROLEUM COMPANY (US) 1980-01-08 US claimed
US-4095030-A CARBOXYLIC ACID SALTS, DILUENTS PHILLIPS PETROLEUM COMPANY (US) 1978-06-13 US claimed
EP-1195393-B1 Process for preparing ethylene interpolymers and ethylene interpolymers obtained therefrom WESTLAKE LONGVIEW CORP (US) 2010-04-07 EP disclosed
US-7241857-B2 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2007-07-10 US disclosed
US-7173157-B2 Method for producing an allyl compound MITSUBISHI CHEMICAL CORPORATION (JP) 2007-02-06 US disclosed
US-7119222-B2 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2006-10-10 US disclosed
US-20060106181-A1 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2006-05-18 US disclosed
US-20050075518-A1 Method for producing allyl compound, and allyl compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2005-04-07 US disclosed
US-20040147757-A1 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2004-07-29 US disclosed
US-6090900-A Polymers containing functionalized olefin monomers EASTMAN CHEMICAL COMPANY (US) 2000-07-18 US disclosed
EP-0963386-A1 POLYMERS CONTAINING FUNCTIONALIZED OLEFIN MONOMERS EASTMAN CHEMICAL COMPANY (US) 1999-12-15 EP disclosed
WO-1998037110-A1 POLYMERS CONTAINING FUNCTIONALIZED OLEFIN MONOMERS EASTMAN CHEMICAL COMPANY (US) 1998-08-27 WO disclosed
US-4238356-A REACTION PRODUCT OF A CARBOXYLIC ACID, SELENIUM DIOXIDE, A HYDROXIDE OR ACID SALT, AND AN ACID ANHYDRIDE PHILLIPS PETROLEUM COMPANY (US) 1980-12-09 US disclosed
US-4182901-A AND SUITABLE CARBOXYLIC ACID PHILLIPS PETROLEUM COMPANY (US) 1980-01-08 US disclosed
US-4095030-A CARBOXYLIC ACID SALTS, DILUENTS PHILLIPS PETROLEUM COMPANY (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060106181-A1 Method for producing allyl compound, and ether or ester compound produced thereby AGPAT5, TST, AGPAT2 LMNA 4141/4885SCN4A 2964/4885MAOA 2224/4885
US-20040147757-A1 Method for producing allyl compound, and ether or ester compound produced thereby AGPAT5, TST, AGPAT2 LMNA 4141/4885SCN4A 2964/4885MAOA 2224/4885
US-20050075518-A1 Method for producing allyl compound, and allyl compound produced thereby CCNT1, AOC3, ATL3 LMNA 3467/4885SCN4A 3660/4885MAOA 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.