SCHEMBL1240940

SCHEMBL1240940

CCOc1ccc(CCO)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.61
CYP4F2 P78329 1/20 0.52
CYP4A11 Q02928 1/20 0.52
LTA4H P09960 2/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ACACB O00763 2/20 0.49
SLC5A1 P13866 1/20 0.49
SLC5A2 P31639 1/20 0.49
PPARA Q07869 1/20 0.49
CA2 P00918 1/20 0.48
GPR84 Q9NQS5 1/20 0.47
HRH3 Q9Y5N1 1/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5671708 0.88 LTA4H (0.61) NQO1CYP4A11LTA4HTSHRTDP1
Phenetole SCHEMBL1867157 0.86 TDP1 (0.61) NQO1CYP4F2CYP4A11LTA4HTDP1
SCHEMBL9026418 0.86 KMT2A (0.55) NQO1CYP4F2CYP4A11LTA4HTSHR
SCHEMBL10610791 0.84 KMT2A (0.58) NQO1CYP4F2CYP4A11LTA4HACACB
SCHEMBL1240693 0.83 LMNA (0.64) LTA4HACACBSLC5A1SLC5A2HRH3
SCHEMBL7837295 0.83 ALDH1A1 (0.66) LTA4HHRH3MEN1USP2ALDH1A1
SCHEMBL131727 0.82 NQO1 (0.67) NQO1LTA4HTSHRTDP1ALDH1A1
SCHEMBL6658231 0.82 HRH3 (0.59) CYP4F2CYP4A11LTA4HTDP1PPARA
SCHEMBL4248652 0.82 NQO1 (0.67) NQO1LTA4HTSHRTDP1ACACB
SCHEMBL7753262 0.82 NQO1 (0.67) NQO1LTA4HTSHRTDP1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083864-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING BAYER AG (DE) 2026-03-26 US disclosed
EP-4583926-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING Bayer Aktiengesellschaft (DE) 2025-07-16 EP disclosed
EP-4308551-B1 NEW CONTRAST AGENT FOR USE IN MAGNETIC RESONANCE IMAGING BAYER AG (DE) 2025-04-09 EP disclosed
US-20240182431-A1 NEW CONTRAST AGENT FOR USE IN MAGNETIC RESONANCE IMAGING BAYER AKTIENGESELLSCHAFT (DE) 2024-06-06 US disclosed
WO-2024052550-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING BAYER AKTIENGESELLSCHAFT (DE) 2024-03-14 WO disclosed
EP-4335462-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING Bayer AG (DE) 2024-03-13 EP disclosed
EP-4308551-A1 NEW CONTRAST AGENT FOR USE IN MAGNETIC RESONANCE IMAGING Bayer Aktiengesellschaft (DE) 2024-01-24 EP disclosed
WO-2023216753-A1 IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE 上海赛默罗生物科技有限公司 2023-11-16 WO disclosed
CN-116981658-A Novel contrast agents for magnetic resonance imaging 拜耳股份有限公司 2023-10-31 CN disclosed
WO-2022194777-A1 NEW CONTRAST AGENT FOR USE IN MAGNETIC RESONANCE IMAGING BAYER AKTIENGESELLSCHAFT (DE) 2022-09-22 WO disclosed
US-5853878-A Elastic fiber, process for the same and polyester elastomer used thereof TEIJIN LIMITED (JP) 1998-12-29 US disclosed
EP-0393607-B1 Phenylcarboxylic acid derivatives having a hetero ring OTSUKA PHARMA CO LTD (JP) 1996-02-21 EP disclosed
EP-0364517-B1 PREVENTION OF PROSTHESIS CALCIFICATION BIOMEDICAL DESIGN INC (US) 1994-04-06 EP disclosed
US-5145865-A Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1992-09-08 US disclosed
EP-0452002-A2 Thienopyrimidine derivatives DOWELANCO (US) 1991-10-16 EP disclosed
EP-0364517-A4 PREVENTION OF PROSTHESIS CALCIFICATION 1991-01-16 EP disclosed
US-4976733-A USING ALIPHATIC CARBOXYLIC ACID BIOMEDICAL DESIGN, INC. (US) 1990-12-11 US disclosed
EP-0393607-A2 Phenylcarboxylic acid derivatives having a hetero ring OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0364517-A1 PREVENTION OF PROSTHESIS CALCIFICATION. BIOMEDICAL DESIGN INC (US) 1990-04-25 EP disclosed
WO-1989006945-A1 PREVENTION OF PROSTHESIS CALCIFICATION BIOMEDICAL DESIGN, INC. (US) 1989-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182431-A1 NEW CONTRAST AGENT FOR USE IN MAGNETIC RESONANCE IMAGING MAG, GBA1, GLRX3 NQO1 2970/4885CYP4F2 2385/4885CYP4A11 4781/4885
US-20260083864-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING CA13, CCR1, GALC NQO1 3399/4885CYP4F2 1479/4885CYP4A11 4088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.