Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537996 | 1.00 | ACKR3 (0.84) | ACKR3 | |
| SCHEMBL3537991 | 1.00 | ACKR3 (0.84) | ACKR3 | |
| SCHEMBL3537993 | 1.00 | ACKR3 (0.84) | ACKR3 | |
| SCHEMBL3586803 | 0.91 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL3586804 | 0.91 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL3540796 | 0.90 | ACKR3 (0.72) | ACKR3 | |
| SCHEMBL12410263 | 0.90 | ACKR3 (0.72) | ACKR3 | |
| SCHEMBL3540792 | 0.90 | ACKR3 (0.72) | ACKR3 | |
| SCHEMBL3540794 | 0.90 | ACKR3 (0.72) | ACKR3 | |
| SCHEMBL3595726 | 0.89 | ACKR3 (0.70) | ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110165164-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND TREATING DISEASES AND CONDITIONS RELATED TO CHEMOKINE RECEPTORS | CHEMOCENTRYX, INC. (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110052589-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND TREATING DISEASES AND CONDITIONS RELATED TO CHEMOKINE RECEPTORS | CHEMOCENTRYX, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110052589-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND TREATING DISEASES AND CONDITIONS RELATED TO CHEMOKINE RECEPTORS | CHEMOCENTRYX, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-7871619-B2 | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | CHEMOCENTRYX, INC. (US) | 2011-01-18 | — | — | US | disclosed |
| US-7871619-B2 | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | CHEMOCENTRYX, INC. (US) | 2011-01-18 | — | — | US | disclosed |
| US-20100247540-A1 | Methods and Compositions For Modulating Angiogenesis | CHEMOCENTRYX, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100247540-A1 | Methods and Compositions For Modulating Angiogenesis | CHEMOCENTRYX, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-7777009-B2 | Compositions for detecting and treating diseases and conditions related to chemokine receptors | CHEMOCENTRYX, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100144720-A1 | INHIBITORS OF HUMAN TUMOR-EXPRESSED CCXCKR2 | CHEMOCENTRYX, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100144720-A1 | INHIBITORS OF HUMAN TUMOR-EXPRESSED CCXCKR2 | CHEMOCENTRYX, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-7649011-B2 | Active against cancer proliferation, growth, and metastasis; such as 3,4,5-trimethoxy-n-(2-methyl-3-phenyl-allyl)-n-[2-(1-methyl-pyrrolidin-2-yl)-thyl]-benzamide; side effect reduction | CHEMOCENTRYX, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7649011-B2 | Active against cancer proliferation, growth, and metastasis; such as 3,4,5-trimethoxy-n-(2-methyl-3-phenyl-allyl)-n-[2-(1-methyl-pyrrolidin-2-yl)-thyl]-benzamide; side effect reduction | CHEMOCENTRYX, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20090054630-A1 | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | CHEMOCENTRYX, INC. | 2009-02-26 | — | — | US | disclosed |
| US-7253007-B2 | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | CHEMOCENTRYX, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253007-B2 | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | CHEMOCENTRYX, INC. (US) | 2007-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165164-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND TREATING DISEASES AND CONDITIONS RELATED TO CHEMOKINE RECEPTORS | CXCR3, CXCR2, ACKR3 | ACKR3 3/4885 |
| US-20090054630-A1 | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | CXCR3, CCR2, CCL2 | ACKR3 7/4885 |
| US-20110052589-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND TREATING DISEASES AND CONDITIONS RELATED TO CHEMOKINE RECEPTORS | CXCR3, CXCR2, ACKR3 | ACKR3 3/4885 |
| US-20100144720-A1 | INHIBITORS OF HUMAN TUMOR-EXPRESSED CCXCKR2 | CCL2, CCR2, CXCR2 | ACKR3 12/4885 |
| US-20100247540-A1 | Methods and Compositions For Modulating Angiogenesis | VEGFA, FLT4, PGF | ACKR3 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.