SCHEMBL12410558

SCHEMBL12410558

CCCc1cc(SC)cc(SC)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
SLC6A4 P31645 7/20 0.35
PTGS2 P35354 3/20 0.32
CYP3A4 P08684 2/20 0.32
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16951694 0.87 FFAR4 (0.37) CNR1CNR2SLC6A4NPC1HPGD
SCHEMBL12410556 0.86 HPGD (0.47) PTGS2CYP3A4NPC1HPGDMAPK1
SCHEMBL16951691 0.85 SLC6A4 (0.31) CNR1CNR2SLC6A4
SCHEMBL16956233 0.85 CNR1 (0.34) CNR1CNR2SLC6A4PTGS2CYP3A4
SCHEMBL12410561 0.82 PTGS2 (0.53) SLC6A4PTGS2CYP3A4LPLLIPG
SCHEMBL21727727 0.82 PTGS2 (0.45) PTGS2CYP3A4NPC1ALDH1A1
SCHEMBL16960311 0.82 CNR1 (0.32) CNR1CNR2
SCHEMBL16955227 0.80 THRB (0.32)
SCHEMBL9886162 0.80 IDO1 (0.35) SLC6A4NPSR1ALDH1A1
SCHEMBL16956230 0.80 CNR1 (0.32) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES CNR1 4238/4885CNR2 4489/4885SLC6A4 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.