Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15710240 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1DRD1ESR1 | |
| SCHEMBL14603771 | 0.88 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TDP1TSHRACHE | |
| SCHEMBL22831360 | 0.88 | TDP1 (0.52) | ALDH1A1CYP3A4TDP1DRD1ESR1 | |
| SCHEMBL49618 | 0.88 | CYP3A4 (0.52) | ALDH1A1CYP3A4TDP1DRD1ESR1 | |
| SCHEMBL29535212 | 0.88 | CYP3A4 (0.52) | ALDH1A1CYP3A4TDP1DRD1ESR1 | |
| SCHEMBL14604091 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1TSHRACHE | |
| SCHEMBL16424436 | 0.86 | CYP3A4 (0.50) | ALDH1A1CYP3A4TDP1DRD1ESR1 | |
| Hydrochloric Acid SCHEMBL10793333 | 0.84 | CYP3A4 (0.48) | ALDH1A1CYP3A4TDP1DRD1ESR1 | |
| SCHEMBL29482776 | 0.83 | TDP1 (0.52) | ALDH1A1CYP3A4TDP1DRD1ESR1 | |
| SCHEMBL1683369 | 0.83 | TDP1 (0.52) | ALDH1A1CYP3A4TDP1DRD1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707553-B2 | P-chirogenic organophosphorus compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-07-18 | — | — | US | disclosed |
| EP-3150613-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-04-05 | — | — | EP | disclosed |
| US-20160023199-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | SYNTHELOR SAS (FR) | 2016-01-28 | — | — | US | disclosed |
| US-9186661-B2 | P-chirogenic organophosphorus compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-11-17 | — | — | US | disclosed |
| US-20140142325-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) (FR) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023199-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | ACHE, PTMS, DDT | ALDH1A1 2686/4885CYP3A4 431/4885TDP1 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.