Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 9/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062364 | 0.80 | ADORA3 (0.55) | ADORA3SLC6A3NOS1ALDH1A1HPGD | |
| SCHEMBL3474793 | 0.80 | ADORA3 (0.55) | ADORA3SLC6A3NOS1ALDH1A1HPGD | |
| SCHEMBL28327828 | 0.80 | ADORA3 (0.55) | ADORA3SLC6A3NOS1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28327830 | 0.78 | ADORA3 (0.53) | ADORA3SLC6A3NOS1ALDH1A1HPGD | |
| SCHEMBL11605900 | 0.77 | ADORA3 (0.51) | ADORA3SLC6A3NOS1ALDH1A1HPGD | |
| SCHEMBL1348513 | 0.76 | CA2 (0.40) | ADORA3SLC6A3CA2CA1CA12 | |
| SCHEMBL30307792 | 0.76 | CA2 (0.37) | ADORA3SLC6A3CA2CA1CA12 | |
| SCHEMBL5515612 | 0.76 | CA2 (0.44) | ADORA3SLC6A3CA2CA1CA12 | |
| SCHEMBL1063493 | 0.75 | ADORA3 (0.50) | ADORA3SLC6A3NOS1ALDH1A1HPGD | |
| SCHEMBL2649270 | 0.75 | ADORA3 (0.50) | ADORA3SLC6A3NOS1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111690171-B | Flame retardant and flame-retardant PC plastic | 广州森赛逖康化工科技有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-111690171-A | Flame retardant and flame-retardant PC plastic | 宁波保税区君一汽配科技有限公司 | 2020-09-22 | — | — | CN | claimed |
| EP-1851225-B1 | PYRAZOLO-PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2011-06-15 | — | — | EP | claimed |
| JP-2008530042-A | — | — | 2008-08-07 | — | — | JP | claimed |
| US-7361659-B2 | Pyrrazolo-pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2008-04-22 | — | — | US | claimed |
| EP-1851225-A1 | PYRAZOLO-PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS | F. Hoffmann-Roche AG (CH) | 2007-11-07 | — | — | EP | claimed |
| US-20060183756-A1 | Pyrrazolo-pyrimidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-08-17 | — | — | US | claimed |
| WO-2006084634-A1 | PYRAZOLO-PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-17 | — | — | WO | claimed |
| CN-111433203-B | Enantiomer of substituted thiazoles as antiviral compounds | 创新分子股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4209491-A1 | ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS | Innovative Molecules GmbH (DE) | 2023-07-12 | — | — | EP | disclosed |
| EP-3692039-B1 | ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS | INNOVATIVE MOLECULES GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |
| CN-109071473-B | Antiviral compounds | 创新分子股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-111690171-B | Flame retardant and flame-retardant PC plastic | 广州森赛逖康化工科技有限公司 | 2022-07-05 | — | — | CN | disclosed |
| US-20220152008-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | INNOVATIVE MOLECULES GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| WO-2003007946-A1 | SECONDARY 1,3-THIAZOLE-5-YL SULFONAMIDE DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-30 | — | — | WO | disclosed |
| US-6500817-B1 | HERPES SIMPLEX | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1244641-A1 | THIAZOLYL AMIDE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2002-10-02 | — | — | EP | disclosed |
| EP-1161423-A1 | THIAZOLYL UREA DERIVATIVES AND THEIR UTILIZATION AS ANTIVIRAL AGENTS | Bayer Aktiengesellschaft (DE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001047904-A1 | THIAZOLYL AMIDE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2000053591-A1 | THIAZOLYL UREA DERIVATIVES AND THEIR UTILIZATION AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220152008-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | EIF2AK2, MAVS, ZC3HAV1 | ADORA3 669/4885SLC6A3 1548/4885NOS1 4327/4885 |
| US-20060183756-A1 | Pyrrazolo-pyrimidine derivatives | GRM1, GRM2, GRM3 | ADORA3 61/4885SLC6A3 1417/4885NOS1 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.