Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15305694 | 0.84 | CYP1A2 (0.62) | L3MBTL1APOBEC3AAPOBEC3GCYP1A2CYP2C19 | |
| SCHEMBL16608839 | 0.81 | LMNA (0.46) | L3MBTL1APOBEC3AAPOBEC3GCYP1A2CYP2C19 | |
| SCHEMBL12411159 | 0.78 | NOS3 (0.48) | L3MBTL1CYP1A2CYP2C19OGG1MAPK1 | |
| SCHEMBL3097555 | 0.77 | MAPK1 (0.47) | L3MBTL1CYP1A2CYP2C19CYP2C9MAPK1 | |
| SCHEMBL12410776 | 0.76 | LMNA (0.52) | L3MBTL1CYP1A2CYP2C19MAPK1MAPT | |
| SCHEMBL27808082 | 0.75 | MAPK1 (0.46) | L3MBTL1CYP1A2CYP2C19CYP2C9OGG1 | |
| SCHEMBL1180045 | 0.73 | MAPK1 (0.47) | L3MBTL1CYP1A2CYP2C19OGG1MAPK1 | |
| SCHEMBL11463095 | 0.73 | CYP1A2 (0.70) | L3MBTL1APOBEC3AAPOBEC3GCYP1A2CYP2C19 | |
| SCHEMBL4552543 | 0.73 | L3MBTL1 (0.59) | L3MBTL1APOBEC3AAPOBEC3GCYP1A2CYP2C19 | |
| SCHEMBL3094255 | 0.72 | MAPK1 (0.59) | L3MBTL1CYP1A2CYP2C19MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289013-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SUNOVION PHARMACEUTICALS INC. | 2013-10-31 | — | — | US | disclosed |
| US-20110166146-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166146-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | PAICS, ITPA, DPYD | L3MBTL1 4640/4885APOBEC3A 3042/4885APOBEC3G 3569/4885 |
| US-20130289013-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | PAICS, ITPA, DPYD | L3MBTL1 4640/4885APOBEC3A 3042/4885APOBEC3G 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.