SCHEMBL1241178

SCHEMBL1241178

CC1=Cc2c(-c3ccccc3)cccc2C1C[SiH2]CC1C(C)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
HTR7 P34969 1/20 0.30
BRD4 O60885 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3997096 0.98 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4
SCHEMBL21963541 0.96 PDCD1 (0.33) PDCD1CD274
SCHEMBL8405197 0.88 MAOA (0.30)
SCHEMBL6648872 0.87 DRD1 (0.35) HTR2A
SCHEMBL8402356 0.86 EDNRB (0.34)
SCHEMBL5609036 0.86 PDCD1 (0.33) PDCD1CD274
SCHEMBL4623138 0.86 PDCD1 (0.39) PDCD1CD274CHRNB2CHRNA4HTR7
SCHEMBL5084813 0.86 PDCD1 (0.39) PDCD1CD274CHRNB2CHRNA4HTR7
SCHEMBL6030145 0.85 BRD4 (0.33) BRD4
SCHEMBL6650592 0.85 PBRM1 (0.32) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2307466-B1 CATALYST SYSTEM AND PROCESS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2015-05-20 EP claimed
WO-2001053356-A1 CATALYST SYSTEM WITH A SELECTED TRANSITION METAL: COCATALYST RATIO BASELL POLYOLEFINE GMBH (DE) 2001-07-26 WO claimed
WO-2023085817-A1 METALLOCENE COMPOUND FOR POLYMERIZATION OF ULTRA-HIGH MOLECULAR WEIGHT POLYOLEFIN, AND METHOD FOR PREPARING ULTRA-HIGH MOLECULAR WEIGHT POLYOLEFIN POLYMER USING SAME 주식회사 에스피씨아이 2023-05-19 WO disclosed
US-9815926-B2 Ethylene copolymers, methods for their production, and use EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-11-14 US disclosed
EP-2824107-B1 ANSA-METALLOCENE COMPOUND AND METHOD FOR PREPARING SUPPORTED CATALYST USING SAME LG CHEMICAL LTD (KR) 2017-01-18 EP disclosed
US-20160347893-A1 Ethylene Copolymers, Methods for Their Production, and Use EXXONMOBIL CHEMICAL PATENTS INC. 2016-12-01 US disclosed
EP-2526132-B1 LUBRICATING OIL COMPOSITIONS AND METHOD FOR MAKING THEM EXXONMOBIL CHEM PATENTS INC (US) 2016-11-16 EP disclosed
US-9441060-B2 Ethylene copolymers, methods for their production, and use EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-13 US disclosed
US-9416206-B2 Lubricating oil compositions and method for making them EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-16 US disclosed
EP-2718012-B1 CATALYST SYSTEMS COMPRISING MULTIPLE NON-COORDINATING ANION ACTIVATORS AND METHODS FOR POLYMERIZATION THEREWITH EXXONMOBIL CHEM PATENTS INC (US) 2016-04-27 EP disclosed
EP-2307466-B1 CATALYST SYSTEM AND PROCESS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2015-05-20 EP disclosed
EP-1109839-A1 HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2001-06-27 EP disclosed
WO-2001042351-A1 METHOD OF PREPARATION OF CROSSLINKED BLENDS OF AMORPHOUS AND CRYSTALLINE POLYMERS EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed
WO-2001042350-A1 CROSSLINKED BLENDS OF AMORPHOUS AND CRYSTALLINE POLYMERS AND THEIR APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed
WO-2000012565-A1 HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 2000-03-09 WO disclosed
US-5965678-A Catalyst system based on monoazadiene metal complexes BAYER AG (DE) 1999-10-12 US disclosed
EP-0889059-A1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 1999-01-07 EP disclosed
EP-0593888-B1 Use of a polyolefin composition for injection moulding TARGOR GMBH (DE) 1998-04-22 EP disclosed
EP-0832924-A2 Polyolefin composition for the preparation of non-wovens TARGOR GmbH (DE) 1998-04-01 EP disclosed
EP-0593888-A1 Polyolefin composition for injection moulding of transparent articles with high rigidity HOECHST AKTIENGESELLSCHAFT (DE) 1994-04-27 EP disclosed