Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154189 | 0.85 | MEN1 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8411500 | 0.85 | HSD11B1 (0.35) | TNKS2 | |
| SCHEMBL1241178 | 0.85 | PDCD1 (0.36) | HTR2A | |
| SCHEMBL1241803 | 0.84 | ALDH1A1 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3997096 | 0.84 | PDCD1 (0.35) | — | |
| SCHEMBL4286443 | 0.83 | ALDH1A1 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21963541 | 0.81 | PDCD1 (0.33) | — | |
| SCHEMBL6030145 | 0.79 | BRD4 (0.33) | — | |
| SCHEMBL8405197 | 0.79 | MAOA (0.30) | SLC6A3 | |
| SCHEMBL6648872 | 0.78 | DRD1 (0.35) | DRD1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421090-A2 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | Exxonmobil Chemical Patents Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003002583-A2 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2003-01-09 | — | — | WO | disclosed |