Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573117 | 0.87 | CTSK (0.45) | CTSKCTSSTRPA1APPPPARA | |
| SCHEMBL3379781 | 0.87 | CTSK (0.51) | CTSKCTSSAPPPPARAPPARG | |
| SCHEMBL844407 | 0.87 | CTSK (0.51) | CTSKCTSSAPPPPARAPPARG | |
| SCHEMBL14250689 | 0.87 | CTSK (0.51) | CTSKCTSSAPPPPARAPPARG | |
| SCHEMBL4116995 | 0.87 | CTSK (0.51) | CTSKCTSSAPPPPARAPPARG | |
| SCHEMBL3414715 | 0.87 | CTSK (0.51) | CTSKCTSSAPPPPARAPPARG | |
| SCHEMBL6107389 | 0.86 | CTSK (0.41) | CTSKCTSSTRPA1APPPPARA | |
| SCHEMBL22303774 | 0.86 | CTSK (0.41) | CTSKCTSSTRPA1APPPPARA | |
| SCHEMBL2436816 | 0.86 | CTSS (0.46) | CTSKCTSSTRPA1 | |
| SCHEMBL2836398 | 0.86 | TRPA1 (0.52) | CTSKCTSSTRPA1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884204-B2 | such as (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-3-quinolinyl)phenyl]propionic acid, used for the teratment of inflammatory diseases, arthritis, inflammatory bowel diseases, lupus, multiple syndrome, asthma, psoriasis, allergies, diabetes and cardiovascular diseases | AJINOMOTO CO., INC. (JP) | 2011-02-08 | — | — | US | disclosed |