Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1437500 | 0.98 | ESR1 (0.55) | ESR1KDM4ECYP19A1ESR2ALDH1A1 | |
| SCHEMBL14747883 | 0.83 | ESR1 (0.49) | ESR1KDM4EALDH1A1TP53 | |
| SCHEMBL9651856 | 0.83 | IDO1 (0.44) | ESR1KDM4EESR2TP53ALOX15 | |
| SCHEMBL8864262 | 0.81 | ESR1 (0.59) | ESR1ALDH1A1 | |
| SCHEMBL7819533 | 0.81 | SMN1; SMN2 (0.54) | ESR1KDM4EALDH1A1 | |
| SCHEMBL11071449 | 0.80 | ESR1 (0.58) | ESR1 | |
| Hydrochloric Acid SCHEMBL21595757 | 0.79 | SMN1; SMN2 (0.53) | ESR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL25374226 | 0.79 | PRSS1 (0.50) | KDM4ECYP1A2CYP3A4 | |
| SCHEMBL11796987 | 0.79 | ESR1 (0.61) | ESR1CYP3A4TP53ALOX15 | |
| SCHEMBL9697402 | 0.79 | ESR1 (0.61) | ESR1CYP3A4TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921382-B2 | Thiazolo[5,4-d] pyrimidines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921382-B2 | Thiazolo[5,4-d] pyrimidines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-12-30 | — | — | US | disclosed |
| EP-2521452-B1 | THIAZOLO[5,4-d]PYRIMIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2014-12-24 | — | — | EP | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| WO-2011085084-A1 | THIAZOLO[5,4-d] PYRIMIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20110166164-A1 | THIAZOLO[5,4-d] PYRIMIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC | 2011-07-07 | — | — | US | disclosed |
| US-20110166164-A1 | THIAZOLO[5,4-d] PYRIMIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC | 2011-07-07 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | CBR3, CBR1, AKR1C4 | ESR1 3635/4885KDM4E 354/4885CYP19A1 1435/4885 |
| US-20110166164-A1 | THIAZOLO[5,4-d] PYRIMIDINES AND THEIR USE AS AGROCHEMICALS | DPYD, TYMS, TYMP | ESR1 2448/4885KDM4E 1753/4885CYP19A1 2544/4885 |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | PIR, PFAS, PNPO | ESR1 2033/4885KDM4E 917/4885CYP19A1 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.