Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864262 | 0.91 | ESR1 (0.59) | ESR1LTA4HMAPTMEN1ALDH1A1 | |
| SCHEMBL11071449 | 0.89 | ESR1 (0.58) | ESR1LTA4HTHRATHRB | |
| SCHEMBL9699080 | 0.87 | ESR1 (0.61) | ESR1LTA4HMAPTMEN1TP53 | |
| SCHEMBL9697402 | 0.87 | ESR1 (0.61) | ESR1LTA4HMAPTMEN1TP53 | |
| SCHEMBL11796987 | 0.87 | ESR1 (0.61) | ESR1LTA4HMAPTMEN1TP53 | |
| SCHEMBL9699688 | 0.87 | ESR1 (0.61) | ESR1LTA4HMAPTMEN1TP53 | |
| SCHEMBL9651856 | 0.85 | IDO1 (0.44) | ESR1MAPTKDM4EMEN1TP53 | |
| SCHEMBL17549596 | 0.85 | LTA4H (0.47) | ESR1LTA4HATMMAPTKDM4E | |
| SCHEMBL863092 | 0.84 | MAPT (0.51) | ESR1LTA4HATMMAPTKDM4E | |
| SCHEMBL3717467 | 0.84 | ESR1 (0.54) | ESR1LTA4HKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111378259-B | Biodegradable PBAT/PLA composite material and preparation method and application thereof | 叶平山 | 2022-08-23 | — | — | CN | disclosed |
| EP-2275413-B1 | 2,4-di(phenylamino)-pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders | NOVARTIS AG (CH) | 2013-03-06 | — | — | EP | disclosed |