Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14863999 | 0.87 | PKM (0.50) | PKMKMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL13944298 | 0.81 | PLK1 (0.60) | KMT2AMGLLHPGDSMN1; SMN2 | |
| SCHEMBL10759764 | 0.81 | CA1 (0.59) | KMT2AMGLLNPC1RAB9AL3MBTL1 | |
| SCHEMBL22811121 | 0.80 | PKM (0.73) | PKMKMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL6191577 | 0.78 | KMT2A (0.49) | KMT2AMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL277445 | 0.78 | PLK1 (0.51) | KMT2AMGLLNPC1RAB9AL3MBTL1 | |
| SCHEMBL28805020 | 0.78 | MAPT (0.52) | KMT2AMGLLRAB9AL3MBTL1HPGD | |
| SCHEMBL12412448 | 0.77 | KMT2A (0.48) | KMT2AMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13339311 | 0.77 | NPC1 (0.46) | PKMKMT2AMGLLNPC1RAB9A | |
| SCHEMBL12410591 | 0.77 | PKM (0.41) | PKMKMT2AMGLLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110165112-A1 | POLYMER CONJUGATES OF C-PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165112-A1 | POLYMER CONJUGATES OF C-PEPTIDES | IAPP, GCG, INSR | PKM 3915/4885KMT2A 4468/4885MGLL 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.