Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12412686 | 0.86 | KDM4E (0.45) | HRH3PPARGPPARDPPARA | |
| SCHEMBL12412543 | 0.83 | HRH3 (0.43) | HTR1AHRH3PPARGPPARDPPARA | |
| SCHEMBL12412689 | 0.82 | CYP2C9 (0.49) | HRH3PPARGPPARDPPARADRD2 | |
| SCHEMBL12503462 | 0.82 | HTR1A (0.49) | HTR1AHTR7GLADRD4DRD2 | |
| SCHEMBL18937702 | 0.81 | HTR1A (0.48) | HTR1AHRH3HTR7DRD3HDAC6 | |
| SCHEMBL2113038 | 0.79 | HTR1A (0.71) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL12041659 | 0.77 | HTR1A (0.51) | HTR1AHRH3HTR7DRD4DRD2 | |
| SCHEMBL19959013 | 0.76 | HRH3 (0.54) | HTR1AHRH3DRD2DRD3 | |
| SCHEMBL381875 | 0.76 | HTR1A (0.50) | HTR1AHRH3HTR7DRD4DRD2 | |
| SCHEMBL11989608 | 0.75 | HRH4 (0.47) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | TOP2B, TOP1, POLI | HTR1A 2692/4885HRH3 3618/4885PPARG 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.