Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12412693 | 0.86 | HTR1A (0.48) | PPARGPPARDPPARAHRH3 | |
| SCHEMBL21780812 | 0.83 | ALDH1A1 (0.49) | KDM4EMDM2ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL19145347 | 0.81 | KDM4E (0.49) | KDM4EMDM2ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL18088545 | 0.80 | ALDH1A1 (0.47) | KDM4EMDM2ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL19105532 | 0.79 | ALDH1A1 (0.50) | KDM4EMDM2ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL12412689 | 0.79 | CYP2C9 (0.49) | KDM4EPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL7356339 | 0.78 | ALDH1A1 (0.66) | KDM4EMDM2ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL12458941 | 0.77 | MEN1 (0.48) | ALDH1A1SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL11916032 | 0.77 | HRH3 (0.40) | KDM4EPPARGPPARDPPARATDP1 | |
| Hydrochloric Acid SCHEMBL1371732 | 0.76 | ALDH1A1 (0.64) | KDM4EMDM2ALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | TOP2B, TOP1, POLI | KDM4E 315/4885MDM2 2516/4885PPARG 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.