Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602871 | 0.83 | TAAR1 (0.55) | L3MBTL1KDM4EGLAHTR2AMAPT | |
| SCHEMBL8252520 | 0.82 | L3MBTL1 (0.64) | L3MBTL1LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL12317 | 0.82 | L3MBTL1 (0.64) | L3MBTL1LMNAHTR2AALDH1A1MEN1 | |
| SCHEMBL23124725 | 0.81 | CYP1A2 (0.57) | L3MBTL1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL9156034 | 0.81 | L3MBTL1 (0.62) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2312495 | 0.81 | CHRM2 (0.68) | L3MBTL1LMNAKDM4EHTR2AALDH1A1 | |
| SCHEMBL6325754 | 0.81 | L3MBTL1 (0.67) | L3MBTL1KDM4EHTR2AMEN1KMT2A | |
| SCHEMBL2051245 | 0.81 | L3MBTL1 (0.62) | L3MBTL1KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL11304095 | 0.81 | L3MBTL1 (0.67) | L3MBTL1LMNAKDM4EHTR2AALDH1A1 | |
| SCHEMBL556793 | 0.80 | MEN1 (0.64) | L3MBTL1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133098-A2 | PROCESSES TO MAKE CRYSTALLINE FORMS OF (S)-N-(3-AMINO-1-(HYDROXYAMINO)-3-METHYL-1-OXOBUTAN-2-YL)-4- ((4-(((2-METHOXYETHYL)AMINO)METHYL)PHENYL)ETHYNYL)BENZAMIDE SALTS | INTERVET INTERNATIONAL B.V. (NL) | 2025-06-26 | — | — | WO | claimed |
| WO-2025133098-A2 | PROCESSES TO MAKE CRYSTALLINE FORMS OF (S)-N-(3-AMINO-1-(HYDROXYAMINO)-3-METHYL-1-OXOBUTAN-2-YL)-4- ((4-(((2-METHOXYETHYL)AMINO)METHYL)PHENYL)ETHYNYL)BENZAMIDE SALTS | INTERVET INTERNATIONAL B.V. (NL) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025133088-A1 | CRYSTALLINE FORMS OF(S)-N-(3-AMINO-1-(HYDROXYAMINO)-3-METHYL-1-OXOBUTAN-2-YL)-4- ((4-(((2-METHOXYETHYL)AMINO)METHYL)PHENYL)ETHYNYL)BENZAMIDE SALTS | INTERVET INTERNATIONAL B.V. (NL) | 2025-06-26 | — | — | WO | disclosed |
| US-7879808-B2 | potent activity against resistant pneumococci; for treating domestic fowl | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20100210570-A1 | LINCOMYCIN DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2151447-A1 | LINCOMYCIN DERIVATIVES AND ANTIBACTERIAL AGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Meiji Seika Kaisha Ltd. (JP) | 2010-02-10 | — | — | EP | disclosed |
| US-20100029754-A1 | THIOPHENE-CARBOXAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE ENZYME IKK-2 | ASTRAZENECA AB (SW) | 2010-02-04 | — | — | US | disclosed |
| US-7572826-B2 | Thiophene-carboxamide derivatives and their use as inhibitors of the enzyme IKK-2 | ASTRAZENECA AB (SE) | 2009-08-11 | — | — | US | disclosed |
| US-20060058522-A1 | Thiophene-carboxamide derivatives and their use as inhibitors of the enzyme ikk-2 | ASTRAZENECA AB (SE) | 2006-03-16 | — | — | US | disclosed |
| EP-1583755-A1 | THIOPHENE-CARBOXAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE ENZIME IKK-2 | AstraZeneca AB (SE) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004063186-A1 | THIOPHENE-CARBOXAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE ENZIME IKK-2 | ASTRAZENECA AB (SE) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058522-A1 | Thiophene-carboxamide derivatives and their use as inhibitors of the enzyme ikk-2 | NFKBIA, RELA, IKBKE | L3MBTL1 3153/4885CYP1A2 355/4885CYP2D6 819/4885 |
| US-20100210570-A1 | LINCOMYCIN DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | LAS1L, LCLAT1, LYPLA1 | L3MBTL1 24/4885CYP1A2 2117/4885CYP2D6 785/4885 |
| US-20100029754-A1 | THIOPHENE-CARBOXAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE ENZYME IKK-2 | NFKBIA, RELA, IKBKE | L3MBTL1 3153/4885CYP1A2 355/4885CYP2D6 819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.