Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981225 | 0.84 | MIF (0.64) | MAPTLMNAMIFCTSLCTSB | |
| SCHEMBL1178453 | 0.84 | PELI1 (0.59) | MIFCTSLCTSBAPPCHRNA7 | |
| SCHEMBL1178455 | 0.84 | PELI1 (0.59) | MIFCTSLCTSBAPPCHRNA7 | |
| SCHEMBL5981232 | 0.84 | MIF (0.64) | MAPTLMNAMIFCTSLCTSB | |
| SCHEMBL1820391 | 0.81 | CHRNA7 (0.64) | MAPTLMNAIAPPCHRNA7TYR | |
| SCHEMBL676889 | 0.81 | CHRNA7 (0.64) | MAPTLMNAIAPPCHRNA7TYR | |
| SCHEMBL18517696 | 0.80 | MAPT (0.50) | MAPTLMNAIAPPMIFCTSL | |
| SCHEMBL26601267 | 0.78 | MAPT (0.67) | MAPTLMNAIAPPAPPCHRNA7 | |
| SCHEMBL27775762 | 0.77 | TYR (0.72) | MAPTLMNACTSLCTSBCHRNA7 | |
| SCHEMBL20152901 | 0.76 | MAPT (0.50) | MAPTLMNAIAPPMIFAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110165101-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | DYKSTRA ROBERT RICHARD | 2011-07-07 | — | — | US | disclosed |
| US-20110028367-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | DYKSTRA ROBERT RICHARD | 2011-02-03 | — | — | US | disclosed |
| US-20100210495-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | DYKSTRA ROBERT RICHARD | 2010-08-19 | — | — | US | disclosed |
| US-20100040569-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | DYKSTRA ROBERT RICHARD | 2010-02-18 | — | — | US | disclosed |
| US-20090186790-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | DYKSTRA ROBERT RICHARD | 2009-07-23 | — | — | US | disclosed |
| US-7534751-B2 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080171681-A1 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | DYKSTRA ROBERT RICHARD | 2008-07-17 | — | — | US | disclosed |
| US-7368415-B2 | Photo-labile pro-fragrance conjugates | PROCTER & GAMBLE COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070264217-A1 | Photo-labile pro-fragrance conjugates | DYKSTRA ROBERT R | 2007-11-15 | — | — | US | disclosed |
| US-7262156-B2 | Photo-labile pro-fragrance conjugates | PROCTER & GAMBLE COMPANY (US) | 2007-08-28 | — | — | US | disclosed |
| US-20070117740-A1 | Photo-labile pro-fragrance conjugates | DYKSTRA ROBERT R | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165101-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | ERCC5, CUTA, TRPA1 | MAPT 1043/4885LMNA 6/4885IAPP 3337/4885 |
| US-20110028367-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | ERCC5, CUTA, TRPA1 | MAPT 1043/4885LMNA 6/4885IAPP 3337/4885 |
| US-20070117740-A1 | Photo-labile pro-fragrance conjugates | ERCC5, CUTA, TRPA1 | MAPT 1043/4885LMNA 6/4885IAPP 3337/4885 |
| US-20080171681-A1 | 3-(2-hydroxyphenyl)-2-propenamides that react to form a lactone and an amine; laundry detergents, perfumes, shampoos and hair conditioners | CUTA, PSAP, PSENEN | MAPT 1805/4885LMNA 69/4885IAPP 3245/4885 |
| US-20070264217-A1 | Photo-labile pro-fragrance conjugates | ERCC5, CUTA, TRPA1 | MAPT 1043/4885LMNA 6/4885IAPP 3337/4885 |
| US-20090186790-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | ERCC5, CUTA, TRPA1 | MAPT 1043/4885LMNA 6/4885IAPP 3337/4885 |
| US-20100040569-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | ERCC5, CUTA, TRPA1 | MAPT 1043/4885LMNA 6/4885IAPP 3337/4885 |
| US-20100210495-A1 | PHOTO-LABILE PRO-FRAGRANCE CONJUGATES | ERCC5, CUTA, TRPA1 | MAPT 1043/4885LMNA 6/4885IAPP 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.