Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.64 |
| ▸ | TYR | P14679 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | IAPP | P10997 | 1/20 | 0.53 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820391 | 1.00 | CHRNA7 (0.64) | CHRNA7TYRLMNAMAPTBACE1 | |
| SCHEMBL26601267 | 0.85 | MAPT (0.67) | CHRNA7LMNAMAPTBACE1IAPP | |
| SCHEMBL4653701 | 0.84 | CHRNA7 (0.68) | CHRNA7TYRBACE1SYNJ2TTR | |
| SCHEMBL4653698 | 0.84 | CHRNA7 (0.68) | CHRNA7TYRBACE1SYNJ2TTR | |
| SCHEMBL18517696 | 0.83 | MAPT (0.50) | CHRNA7TYRLMNAMAPTBACE1 | |
| SCHEMBL89187 | 0.82 | MIF (0.68) | CHRNA7TYRBACE1 | |
| SCHEMBL28140874 | 0.82 | MIF (0.68) | CHRNA7TYRBACE1 | |
| SCHEMBL28391865 | 0.82 | MIF (0.68) | CHRNA7TYRBACE1 | |
| SCHEMBL471946 | 0.82 | MIF (0.68) | CHRNA7TYRBACE1 | |
| SCHEMBL26046386 | 0.82 | TRIM24 (0.62) | CHRNA7TYRLMNAMAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |
| US-20220002768-A1 | ENZYMATIC SYNTHESIS OF KAVALACTONES AND FLAVOKAVAINS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-01-06 | — | — | US | disclosed |
| US-20220002769-A1 | ENZYMATIC SYNTHESIS OF KAVALACTONES AND FLAVOKAVAINS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-01-06 | — | — | US | disclosed |
| US-20190142940-A1 | Method and system for effecting changes in pigmented tissue | MOAZED KAMBIZ THOMAS (US) | 2019-05-16 | — | — | US | disclosed |
| EP-2686369-B1 | MULTIFUNCTIONAL SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF AND METHODS OF USE | PRC DESOTO INT INC (US) | 2018-12-19 | — | — | EP | disclosed |
| EP-2686370-B1 | TERMINAL-MODIFIED DIFUNCTIONAL SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF AND METHODS OF USE | PRC DESOTO INT INC (US) | 2018-09-26 | — | — | EP | disclosed |
| US-9744237-B2 | Method and system for effecting changes in pigmented tissue | MOAZED KAMBIZ THOMAS (US) | 2017-08-29 | — | — | US | disclosed |
| EP-2758453-B9 | FLEXIBLE POLYAMINES, FLEXIBLE AMINE-TERMINATED ADDUCTS, COMPOSITIONS THEREOF AND METHODS OF USE | PRC DESOTO INT INC (US) | 2016-09-14 | — | — | EP | disclosed |
| US-9422467-B2 | Flexible polyamines, flexible amine-terminated adducts, compositions thereof and methods of use | PRC-DESOTO INTERNATIONAL, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20110280909-A1 | METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE | MOAZED KAMBIZ THOMAS (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110178313-A1 | POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME | OOTAKE NOBUMASA | 2011-07-21 | — | — | US | disclosed |
| US-7939617-B2 | Silsesquioxane derivative; electronic material, optical material, optoelectronic material, paint, and primer. | CHISSO CORPORATION (JP) | 2011-05-10 | — | — | US | disclosed |
| WO-2010087983-A1 | METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE | MOAZED KAMBIZ THOMAS (US) | 2010-08-05 | — | — | WO | disclosed |
| US-20080171846-A1 | Polysiloxane compound and method of producing the same | JNC CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
| US-7319129-B2 | Silsesquioxane derivative and process for producing the same | CHISSO CORPORATION (JP) | 2008-01-15 | — | — | US | disclosed |
| US-7053167-B2 | Silsesquioxane derivative having functional group | CHISSO CORPORATION (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20060089504-A1 | Silsesquioxane derivative having functional group | ITO KENYA | 2006-04-27 | — | — | US | disclosed |
| US-20060052623-A1 | Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance | CHISSO CORPORATION (JP) | 2006-03-09 | — | — | US | disclosed |
| US-20040068074-A1 | Production process for silsesquioxane derivative having functional group and silsesquioxane derivative | JNC CORPORATION (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052623-A1 | Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance | STS, PFAS, POLQ | CHRNA7 1477/4885TYR 907/4885LMNA 2213/4885 |
| US-20110178313-A1 | POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME | RPS4X, POLR2A, MSL1 | CHRNA7 2259/4885TYR 4823/4885LMNA 1175/4885 |
| US-20060089504-A1 | Silsesquioxane derivative having functional group | SFXN1, STS, SRM | CHRNA7 1646/4885TYR 294/4885LMNA 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.