SCHEMBL12415475

SCHEMBL12415475

C=CC1CC(C=C)C(C(=O)OCc2ccccc2)C1C(=O)NCC

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.42
FABP5 Q01469 1/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
ELANE P08246 2/20 0.41
CPB1 P15086 1/20 0.40
TGM2 P21980 1/20 0.39
FKBP1A P62942 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
HTR2C P28335 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12415476 0.91 CA1 (0.41) FABP7FABP5CA1CA2CPB1
SCHEMBL12415474 0.89 ALDH1A1 (0.46) FABP7FABP5CA1CA2TGM2
SCHEMBL12415464 0.88 FABP7 (0.52) FABP7FABP5CA1CA2ALDH1A1
SCHEMBL15592928 0.81 CPB1 (0.42) FABP7FABP5CA1CA2CPB1
SCHEMBL12415458 0.80 FABP7 (0.43) FABP7FABP5CA1CA2CPB1
SCHEMBL8694813 0.70 FABP7 (0.50) FABP7FABP5TGM2ALDH1A1
SCHEMBL8694810 0.70 FABP7 (0.50) FABP7FABP5TGM2ALDH1A1
SCHEMBL19323426 0.70 CA1 (0.63) FABP7FABP5CA1CA2ALDH1A1
SCHEMBL8694818 0.70 FABP7 (0.50) FABP7FABP5TGM2ALDH1A1
SCHEMBL15080034 0.69 TSHR (0.61) CA1CA2CPB1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140080984-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS ZANNA SCITECH CO., LTD. (CN) 2014-03-20 US disclosed
US-20110172381-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS ZANNA SCITECH CO., LTD. (CN) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172381-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS RCSD1, RRP12, TIAM1 FABP7 4747/4885FABP5 4476/4885CA1 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.