SCHEMBL12415482

SCHEMBL12415482

C=CC1CC(C=C)C2C(=O)N(C(C)C)C(=O)C12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
FAAH O00519 1/20 0.31
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23612572 0.78 MEN1 (0.35) MEN1KMT2ASMN1; SMN2ALDH1A1HPGD
SCHEMBL12415477 0.78 ALDH1A1 (0.32) KMT2AALDH1A1
SCHEMBL12415486 0.77 PIK3CD (0.35) MEN1KMT2ASMN1; SMN2ALDH1A1FAAH
SCHEMBL12415492 0.74 ALDH1A1 (0.34) MEN1KMT2ASMN1; SMN2ALDH1A1FAAH
SCHEMBL12534614 0.73 MEN1 (0.35) MEN1KMT2ASMN1; SMN2ALDH1A1HPGD
SCHEMBL12415479 0.73 ALDH1A1 (0.36) MEN1KMT2ASMN1; SMN2ALDH1A1CYP19A1
SCHEMBL19130398 0.73 HSD17B10 (0.36) ALDH1A1
SCHEMBL12534609 0.71 MEN1 (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1HPGD
SCHEMBL12415487 0.70 ALDH1A1 (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1CYP19A1
SCHEMBL12308316 0.69 ALDH1A1 (0.59) MEN1KMT2ASMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140080984-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS ZANNA SCITECH CO., LTD. (CN) 2014-03-20 US disclosed
US-20110172381-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS ZANNA SCITECH CO., LTD. (CN) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172381-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS RCSD1, RRP12, TIAM1 MEN1 1844/4885KMT2A 3970/4885SMN1; SMN2 2598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.