SCHEMBL12415477

SCHEMBL12415477

C=CC1CC(C=C)C2C(=O)N(C)C(=O)C12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18962172 0.88
SCHEMBL12415487 0.79 ALDH1A1 (0.37) ALDH1A1KMT2A
SCHEMBL12415482 0.78 MEN1 (0.33) ALDH1A1KMT2A
SCHEMBL12415479 0.78 ALDH1A1 (0.36) ALDH1A1KMT2A
SCHEMBL19130398 0.78 HSD17B10 (0.36) ALDH1A1
SCHEMBL16077011 0.77
SCHEMBL18069136 0.77
SCHEMBL19601265 0.75
SCHEMBL12415492 0.75 ALDH1A1 (0.34) ALDH1A1KMT2A
SCHEMBL18117671 0.75 ALDH1A1 (0.37) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303776-A1 FULLY AND PARTIALLY BACKBONE-DEGRADABLE POLYMERS VIA LOW TEMPERATURE RING-OPENING METATHESIS POLYMERIZATION (ROMP) NORTHWESTERN UNIVERSITY (US) 2023-09-28 US disclosed
US-9243098-B2 Compound, polymer, cross-linked compound of polymer, and optical element including cross-linked compound CANON KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20140163175-A1 NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND CANON KABUSHIKI KAISHA (JP) 2014-06-12 US disclosed
US-20140080984-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS ZANNA SCITECH CO., LTD. (CN) 2014-03-20 US disclosed
US-20110172381-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS ZANNA SCITECH CO., LTD. (CN) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172381-A1 HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS RCSD1, RRP12, TIAM1 ALDH1A1 3240/4885KMT2A 3970/4885
US-20140163175-A1 NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND PCLAF, PCNA, SMC2 ALDH1A1 3378/4885KMT2A 2483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.