⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078924 | 1.00 | — | — | |
| SCHEMBL19051013 | 1.00 | — | — | |
| SCHEMBL19760424 | 1.00 | — | — | |
| SCHEMBL19078920 | 0.86 | SSTR1 (0.34) | — | |
| SCHEMBL19760422 | 0.86 | SSTR1 (0.34) | — | |
| SCHEMBL10366417 | 0.85 | FGF1 (0.31) | — | |
| SCHEMBL18294595 | 0.85 | FGF1 (0.33) | — | |
| SCHEMBL19051014 | 0.85 | FGF1 (0.33) | — | |
| SCHEMBL25605193 | 0.85 | FGF1 (0.33) | — | |
| SCHEMBL25594520 | 0.85 | FGF1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026357-A1 | MODIFIED MIR-135, CONJUGATED FORM THEREOF, AND USES OF SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2024-01-25 | — | — | US | disclosed |
| US-9409934-B2 | Cyclohexenyl nucleic acids analogs | IONIS PHARMACEUTICALS, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20140073786-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-20110172294-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | IONIS PHARMACEUTICALS, INC. | 2011-07-14 | — | — | US | disclosed |