SCHEMBL19760422

SCHEMBL19760422

COC[C@H]1O[C@@H](C)C(OCCN)[C@H]1OC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SSTR1 P30872 1/20 0.34
▸ SSTR2 P30874 1/20 0.34
▸ SSTR4 P31391 1/20 0.34
▸ SSTR3 P32745 1/20 0.34
▸ SSTR5 P35346 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19078920 1.00 SSTR1 (0.34) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL12416160 0.86 — —
SCHEMBL19051013 0.86 — —
SCHEMBL19760424 0.86 — —
SCHEMBL19078924 0.86 — —
SCHEMBL10366417 0.82 FGF1 (0.31) —
SCHEMBL25594520 0.82 FGF1 (0.33) —
SCHEMBL18294595 0.82 FGF1 (0.33) —
SCHEMBL19051014 0.82 FGF1 (0.33) —
SCHEMBL25594518 0.82 FGF1 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026360-A1 OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION HOFFMANN LA ROCHE (US) 2024-01-25 — — US disclosed
US-20230257748-A1 USE OF A1CF INHIBITORS FOR TREATING HEPATITIS B VIRUS INFECTION HOFFMANN-LA ROCHE INC. (US) 2023-08-17 — — US disclosed
US-11667660-B2 Pyridinium salts as activators in the synthesis of stereodefined oligonucleotides ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2023-06-06 — — US disclosed
US-20230132093-A1 EXTRACELLULAR VESICLE-NLRP3 ANTAGONIST CODIAK BIOSCIENCES, INC. (US) 2023-04-27 — — US disclosed
US-20180002701-A1 ANTISENSE OLIGONUCLEOTIDES FOR MODULATING HTRA1 EXPRESSION HOFFMANN-LA ROCHE INC. 2018-01-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132093-A1 EXTRACELLULAR VESICLE-NLRP3 ANTAGONIST NLRP3, MTREX, NOD1 SSTR1 3967/4885SSTR2 4009/4885SSTR4 3924/4885
US-11667660-B2 Pyridinium salts as activators in the synthesis of stereodefined oligonucleotides RNGTT, CPSF6, NUDT1 SSTR1 1405/4885SSTR2 2198/4885SSTR4 806/4885
US-20230257748-A1 USE OF A1CF INHIBITORS FOR TREATING HEPATITIS B VIRUS INFECTION BCDIN3D, SNRPF, U2AF2 SSTR1 4350/4885SSTR2 4089/4885SSTR4 3398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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