Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074908 | 0.95 | FDPS (0.41) | FDPSALDH1A1SMPD1SMN1; SMN2TNNC1 | |
| SCHEMBL10686382 | 0.91 | FDPS (0.39) | FDPSALDH1A1SMPD1SMN1; SMN2TNNC1 | |
| SCHEMBL19283464 | 0.84 | FDPS (0.39) | FDPSALDH1A1SMPD1SMN1; SMN2DNM1 | |
| SCHEMBL11612056 | 0.84 | FDPS (0.42) | FDPSALDH1A1SMPD1DNM1LMNA | |
| SCHEMBL165249 | 0.84 | ALDH1A1 (0.42) | FDPSALDH1A1SMN1; SMN2TNNC1SGPL1 | |
| SCHEMBL227493 | 0.84 | ALDH1A1 (0.42) | FDPSALDH1A1SMN1; SMN2TNNC1SGPL1 | |
| SCHEMBL2346689 | 0.84 | ALDH1A1 (0.42) | FDPSALDH1A1SMN1; SMN2TNNC1SGPL1 | |
| Ammonia Solution, Strong SCHEMBL5707582 | 0.81 | ALDH1A1 (0.40) | FDPSALDH1A1SMN1; SMN2TNNC1SGPL1 | |
| SCHEMBL5607589 | 0.79 | DNM1 (0.39) | FDPSALDH1A1SMPD1DNM1MEN1 | |
| SCHEMBL21161 | 0.79 | ALDH1A1 (0.38) | FDPSALDH1A1SMN1; SMN2TNNC1SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276772-B1 | BORON OR ALUMINUM COMPLEXES | CENTRE NAT RECH SCIENT (FR) | 2014-08-20 | — | — | EP | disclosed |
| US-8563761-B2 | Boron or aluminum complexes | CENTRE NATIONAL DE LA RECHERCHE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-8563761-B2 | Boron or aluminum complexes | CENTRE NATIONAL DE LA RECHERCHE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-20110171112-A1 | BORON OR ALUMINUM COMPLEXES | UNIVERSITE DE PICARDIE JULES VERNE (FR) | 2011-07-14 | — | — | US | disclosed |
| US-20110171112-A1 | BORON OR ALUMINUM COMPLEXES | UNIVERSITE DE PICARDIE JULES VERNE (FR) | 2011-07-14 | — | — | US | disclosed |
| WO-2009122044-A2 | BORON OR ALUMINUM COMPLEXES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171112-A1 | BORON OR ALUMINUM COMPLEXES | AFF4, AFF2, AFF1 | FDPS 3606/4885ALDH1A1 4333/4885SMPD1 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.