Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 8/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417505 | 0.88 | GLP1R (0.33) | GLP1RROCK2PRKACAAKT3 | |
| SCHEMBL12892953 | 0.85 | ROCK2 (0.44) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16328751 | 0.82 | TLR2 (0.42) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12417646 | 0.81 | ROCK2 (0.32) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16328767 | 0.79 | TLR2 (0.42) | GLP1RROCK2PRKACAAKT3TLR2 | |
| SCHEMBL23077727 | 0.78 | GLP1R (0.49) | GLP1RFOLH1 | |
| SCHEMBL15919171 | 0.78 | GLP1R (0.49) | GLP1RFOLH1 | |
| SCHEMBL17287165 | 0.78 | GLP1R (0.49) | GLP1RFOLH1 | |
| SCHEMBL22967415 | 0.78 | GLP1R (0.46) | GLP1RFOLH1 | |
| SCHEMBL12892897 | 0.78 | GLP1R (0.39) | PLGPRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450097-B2 | Protein-proteophore complexes | ASCENDIS PHARMA GMBH (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20110172390-A1 | Protein-Proteophore Complexes | ASCENDIS PHARMA A/S (DK) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172390-A1 | Protein-Proteophore Complexes | PSMG3, PSME1, PSMD11 | PLG 417/4885PRSS1 479/4885PRSS2 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.