SCHEMBL22967415

SCHEMBL22967415

O=C(CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NCCCC[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)C(=O)NCCOS

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.46
▸ FOLH1 Q04609 5/20 0.36
▸ EPOR P19235 2/20 0.34
▸ PLK1 P53350 1/20 0.34
▸ AKT1 P31749 1/20 0.33
▸ MGLL Q99685 1/20 0.33
▸ SIRT2 Q8IXJ6 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22967376 0.93 GLP1R (0.42) GLP1RFOLH1PLK1AKT1MGLL
SCHEMBL16329790 0.91 GLP1R (0.51) GLP1RFOLH1EPORPLK1
SCHEMBL19541810 0.91 GLP1R (0.51) GLP1RFOLH1EPORPLK1
SCHEMBL16329599 0.91 GLP1R (0.51) GLP1RFOLH1EPORPLK1
SCHEMBL19541901 0.91 GLP1R (0.50) GLP1RFOLH1AKT1SIRT2
SCHEMBL16329594 0.90 GLP1R (0.52) GLP1RFOLH1EPORPLK1AKT1
SCHEMBL22515210 0.90 GLP1R (0.49) GLP1RFOLH1EPORAKT1SIRT2
SCHEMBL26562244 0.90 GLP1R (0.47) GLP1RFOLH1EPORAKT1SIRT2
SCHEMBL16329539 0.89 GLP1R (0.45) GLP1RFOLH1EPORPLK1AKT1
SCHEMBL19541902 0.88 GLP1R (0.49) GLP1RFOLH1EPORAKT1SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947289-B2 Glyco-modified atrial natriuretic peptide DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-03-16 — — US disclosed
US-20210040170-A1 GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-02-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947289-B2 Glyco-modified atrial natriuretic peptide NPPA, NPR1, NPR3 GLP1R 15/4885FOLH1 2196/4885EPOR 2475/4885
US-20210040170-A1 GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE NPPA, NPR1, NPR3 GLP1R 15/4885FOLH1 2196/4885EPOR 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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