Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289957 | 1.00 | TRPM8 (0.62) | TRPM8EPHX1NAMPTF13A1TGM2 | |
| SCHEMBL15107410 | 0.89 | TRPM8 (0.60) | TRPM8EPHX1NAMPTNPC1RAB9A | |
| SCHEMBL18241834 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1616599 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29007018 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23187800 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20226803 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12422177 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28589008 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28574384 | 0.88 | TRPM8 (0.66) | TRPM8EPHX1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487130-B2 | Menthylcarboxamides and their use as cooling agents | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20110195032-A1 | Menthylcarboxamides and Their Use as Cooling Agents | KAZIMIERSKI ARKADIUSZ | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195032-A1 | Menthylcarboxamides and Their Use as Cooling Agents | GMDS, CHIA, RIMKLA | TRPM8 59/4885EPHX1 1156/4885NAMPT 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.