Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.66 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18241834 | 1.00 | TRPM8 (0.66) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL1616599 | 1.00 | TRPM8 (0.66) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL28574384 | 1.00 | TRPM8 (0.66) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL29007018 | 1.00 | TRPM8 (0.66) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL28589008 | 1.00 | TRPM8 (0.66) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL23187800 | 1.00 | TRPM8 (0.66) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL20226803 | 1.00 | TRPM8 (0.66) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL12715179 | 0.89 | TRPM8 (0.67) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL4889653 | 0.89 | TRPM8 (0.67) | TRPM8EPHX1CYP19A1POLBTSHR | |
| SCHEMBL14022692 | 0.88 | TRPM8 (0.69) | TRPM8EPHX1CYP19A1SERPINE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028893-A | Composition and method for producing the same | 奇华顿股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-3817575-B1 | SOLUBILISATION OF COOLING AGENTS OF LOW SOLUBILITY | SYMRISE AG (DE) | 2025-10-15 | — | — | EP | claimed |
| EP-4192422-B1 | COOLING SENSATION COMPOSITIONS | GIVAUDAN SA (CH) | 2025-06-11 | — | — | EP | claimed |
| WO-2025078256-A1 | COMPOSITION | GIVAUDAN SA (CH) | 2025-04-17 | — | — | WO | claimed |
| WO-2025026525-A1 | HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS | SYMRISE AG (DE) | 2025-02-06 | — | — | WO | claimed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | claimed |
| CN-118984825-A | Novel cooling agent and preparation containing same | 西姆莱斯股份公司 | 2024-11-19 | — | — | CN | claimed |
| EP-4452941-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-10-30 | — | — | EP | claimed |
| US-20240058259-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2024-02-22 | — | — | US | claimed |
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| WO-2018211420-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2018-11-22 | — | — | WO | claimed |
| US-20180057447-A1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2018-03-01 | — | — | US | claimed |
| WO-2018027202-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (USA) (US) | 2018-02-08 | — | — | WO | claimed |
| EP-3275962-A1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | Takasago International Corporation (JP) | 2018-01-31 | — | — | EP | claimed |
| EP-2785309-B1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | HENKEL AG & CO KGAA (DE) | 2017-07-12 | — | — | EP | claimed |
| US-20140348756-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | HENKEL AG & CO. KGAA (DE) | 2014-11-27 | — | — | US | claimed |
| US-20140271518-A1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | HENKEL AG & CO. KGAA (DE) | 2014-09-18 | — | — | US | claimed |
| EP-2758029-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | Henkel AG&Co. KGAA (DE) | 2014-07-30 | — | — | EP | claimed |
| WO-2013041611-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | HENKEL AG & CO. KGAA (DE) | 2013-03-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348756-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | CUTA, RDX, POLR1C | TRPM8 3118/4885EPHX1 673/4885CYP19A1 2873/4885 |
| US-20180057447-A1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TRPM4, TAS2R41, TRPM2 | TRPM8 5/4885EPHX1 1703/4885CYP19A1 732/4885 |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TRPA1, TRPV1, TRPV4 | TRPM8 6/4885EPHX1 1930/4885CYP19A1 949/4885 |
| US-20140271518-A1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | ALOX5, CUTA, OR51E2 | TRPM8 308/4885EPHX1 963/4885CYP19A1 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.