Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HPD | P32754 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12420601 | 0.90 | NR4A2 (0.62) | NR4A2MAOBALDH1A1PARP1SMN1; SMN2 | |
| SCHEMBL12420802 | 0.89 | PARP1 (0.59) | NR4A2MAOBALDH1A1PARP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2195211 | 0.89 | NR4A2 (0.60) | NR4A2MAOBALDH1A1PARP1SMN1; SMN2 | |
| SCHEMBL11085975 | 0.88 | ALDH1A1 (0.74) | NR4A2MAOBALDH1A1PARP1SMN1; SMN2 | |
| SCHEMBL12420848 | 0.84 | NR4A2 (0.47) | NR4A2MAOBPARP1GRM5PARP10 | |
| SCHEMBL12420786 | 0.82 | PARP1 (0.59) | NR4A2MAOBALDH1A1PARP1 | |
| SCHEMBL2336862 | 0.81 | SMN1; SMN2 (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL12420762 | 0.81 | NR4A2 (0.55) | NR4A2MAOBPARP10 | |
| SCHEMBL4413778 | 0.80 | MEN1 (0.67) | NR4A2MAOBALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL222679 | 0.80 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | NR4A2 3133/4885MAOB 222/4885ALDH1A1 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.