Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.65 |
| ▸ | RXRA | P19793 | 2/20 | 0.63 |
| ▸ | RXRB | P28702 | 2/20 | 0.63 |
| ▸ | RXRG | P48443 | 2/20 | 0.63 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.63 |
| ▸ | KDM5A | P29375 | 1/20 | 0.63 |
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837794 | 0.86 | NR4A2 (0.58) | NR4A2KDM5BKDM5AMRGPRX4KDM4C | |
| SCHEMBL4679114 | 0.81 | RXRA (0.67) | NR4A2RXRARXRBRXRGKDM5B | |
| SCHEMBL29784229 | 0.79 | NR4A2 (1.00) | NR4A2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL13802461 | 0.79 | NR4A2 (1.00) | NR4A2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL15779101 | 0.78 | KDM5A (1.00) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL30822604 | 0.77 | GLRA1 (0.51) | NR4A2KDM5BKDM5AKDM4CALKBH1 | |
| SCHEMBL6522344 | 0.77 | RXRA (1.00) | NR4A2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL27189260 | 0.77 | GLRA1 (0.51) | NR4A2KDM5BKDM5AKDM4CALKBH1 | |
| SCHEMBL29784197 | 0.77 | RXRA (1.00) | NR4A2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL698500 | 0.77 | MRGPRX4 (0.80) | NR4A2RXRARXRBRXRGMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | NR4A2 3133/4885RXRA 2656/4885RXRB 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.