Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099420 | 0.84 | NPC1 (0.55) | NPC1CYP2D6MAOAMAOBKDM1A | |
| SCHEMBL12384488 | 0.81 | HDAC1 (0.57) | NPC1CYP2D6MAOAMAOBKDM1A | |
| SCHEMBL8666600 | 0.78 | HDAC1 (0.55) | NPC1CYP1A2CYP3A4CYP2C19MAOA | |
| SCHEMBL5101101 | 0.77 | CYP1A2 (0.53) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8604113 | 0.77 | CYP17A1 (0.55) | NPC1CYP2D6MAOAMAOBKDM1A | |
| SCHEMBL30030142 | 0.77 | CYP17A1 (0.55) | NPC1CYP2D6MAOAMAOBKDM1A | |
| SCHEMBL23023032 | 0.75 | GAA (0.53) | NPC1MAOAMAOBKDM1ACYP19A1 | |
| SCHEMBL29275230 | 0.74 | BACE1 (0.59) | CYP2D6KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29826089 | 0.72 | AHR (0.58) | NPC1MAOAMAOBKDM1ACYP19A1 | |
| SCHEMBL223719 | 0.72 | CYP1A2 (0.76) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207943-A1 | NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | BIOPHORE INDIA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207943-A1 | NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | HTR3C, HTR3A, HTR1A | NPC1 2380/4885CYP2D6 142/4885CYP1A2 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.