Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070336 | 0.86 | ALDH1A1 (0.42) | F2F10PLGPLAUPLAT | |
| SCHEMBL28549913 | 0.86 | MEN1 (0.39) | MEN1KMT2ATDP1PARP1F2 | |
| SCHEMBL15417609 | 0.85 | MEN1 (0.61) | MEN1KMT2ATDP1PARP1RXFP1 | |
| SCHEMBL12903506 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2ATDP1PARP1RXFP1 | |
| SCHEMBL23875051 | 0.79 | CA1 (0.58) | MEN1KMT2ATDP1F2F10 | |
| SCHEMBL8634908 | 0.79 | RAB9A (0.50) | KMT2ATDP1ALDH1A1MAPTHPGD | |
| SCHEMBL8416208 | 0.78 | POLB (0.60) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL6651792 | 0.78 | HPGD (0.53) | KMT2AALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL27393236 | 0.78 | NPC1 (0.62) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL3073042 | 0.77 | PLAU (0.39) | F2F10PLGPLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268052-A1 | PREPARATIONS OF META-IODOBENZYLGUANDINE AND PRECURSORS THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2018-01-17 | — | — | EP | claimed |
| EP-3600453-A1 | RADIOLABELED BIOMOLECULES AND THEIR USE | Duke University (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018178936-A1 | RADIOLABELED BIOMOLECULES AND THEIR USE | DUKE UNIVERSITY (US) | 2018-10-04 | — | — | WO | disclosed |
| EP-3268052-A1 | PREPARATIONS OF META-IODOBENZYLGUANDINE AND PRECURSORS THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2018-01-17 | — | — | EP | disclosed |
| EP-2655295-A1 | RADIOIODINATED GUANIDINES | GE Healthcare UK Limited (GB) | 2013-10-30 | — | — | EP | disclosed |
| EP-2643023-A1 | RADIOIODINATION METHOD | GE Healthcare UK Limited (GB) | 2013-10-02 | — | — | EP | disclosed |
| EP-2509638-A1 | IODINE RADIOLABELLING METHOD | GE Healthcare UK Limited (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2012084928-A1 | RADIOIODINATED GUANIDINES | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| EP-2467365-A1 | RADIOIODINATION METHOD | GE Healthcare Limited (GB) | 2012-06-27 | — | — | EP | disclosed |
| WO-2012069535-A1 | RADIOIODINATION METHOD | GE HEALTHCARE LIMITED (GB) | 2012-05-31 | — | — | WO | disclosed |
| WO-2011070136-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011020907-A1 | RADIOIODINATION METHOD | GE HEALTHCARE LIMITED (GB) | 2011-02-24 | — | — | WO | disclosed |
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008121322-A1 | A METHOD OF TREATING NEUROBLASTOMA | DUKE UNIVERSITY (US) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| EP-1901783-A1 | GENTISIC ACID FOR STABILISIG 123-I RADIOPHARMACEUTICALS | GE Healthcare UK Limited (GB) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007021-A1 | GENTISIC ACID FOR STABILISIG 123-I RADIOPHARMACEUTICALS | GE HEALTHCARE LIMITED (GB) | 2007-01-18 | — | — | WO | disclosed |
| EP-1185316-A1 | DEVICES AND COMPOUNDS FOR TREATING ARTERIAL RESTENOSIS | Cardio Vascular Solutions Inc. (CA) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000074742-A1 | DEVICES AND COMPOUNDS FOR TREATING ARTERIAL RESTENOSIS | CARDIO VASCULAR SOLUTIONS INC. (CA) | 2000-12-14 | — | — | WO | disclosed |