Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424200 | 0.99 | CYP2C8 (0.53) | CYP2C8BACE1SRD5A2RXRARXRB | |
| SCHEMBL17166056 | 0.99 | CYP2C8 (0.53) | CYP2C8BACE1SRD5A2RXRARXRB | |
| SCHEMBL12423989 | 0.99 | CYP2C8 (0.53) | CYP2C8BACE1SRD5A2RXRARXRB | |
| SCHEMBL12424199 | 0.99 | CYP2C8 (0.53) | CYP2C8BACE1SRD5A2RXRARXRB | |
| SCHEMBL12424201 | 0.99 | CYP2C8 (0.53) | CYP2C8BACE1SRD5A2RXRARXRB | |
| SCHEMBL12424198 | 0.99 | CYP2C8 (0.53) | CYP2C8BACE1SRD5A2RXRARXRB | |
| SCHEMBL13410666 | 0.93 | CYP2C8 (0.55) | CYP2C8BACE1SRD5A2RXRARXRB | |
| SCHEMBL12424113 | 0.84 | CNR2 (0.52) | CYP2C8SRD5A2CNR2CNR1AKR1C3 | |
| SCHEMBL13445159 | 0.83 | KIF11 (0.54) | CYP2C8SRD5A2RXRARXRBPPARA | |
| SCHEMBL13445154 | 0.83 | KIF11 (0.54) | CYP2C8SRD5A2RXRARXRBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8449794-B2 | Non-resonant two-photon absorption recording material and non-resonant two-photon absorption compound | FUJIFILM CORPORATION (JP) | 2013-05-28 | — | — | US | disclosed |
| US-8449794-B2 | Non-resonant two-photon absorption recording material and non-resonant two-photon absorption compound | FUJIFILM CORPORATION (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20120319059-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | FUJIFILM CORPORATION (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120319059-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | FUJIFILM CORPORATION (JP) | 2012-12-20 | — | — | US | disclosed |
| WO-2011102545-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | FUJIFILM CORPORATION (JP) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120319059-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | CRY2, KCNJ2, NONO | CYP2C8 3317/4885BACE1 278/4885SRD5A2 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.