Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25606724 | 0.96 | KDM4E (0.36) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL25717698 | 0.94 | KDM4E (0.35) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL25607141 | 0.93 | KDM4E (0.33) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL25717696 | 0.92 | KDM4E (0.36) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL9932623 | 0.92 | KDM4E (0.36) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL25607147 | 0.92 | KDM4E (0.34) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL25607143 | 0.91 | KDM4E (0.33) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL25607138 | 0.90 | KDM4E (0.33) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL29664129 | 0.89 | PGR (0.32) | KDM4EMEN1ALDH1A1LMNACYP2C9 | |
| SCHEMBL1009516 | 0.89 | PGR (0.32) | KDM4EMEN1ALDH1A1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7976739-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7976739-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| EP-2055698-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-20100230649-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100230649-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2055698-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2009-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230649-A1 | CHROMENE COMPOUND | CCNT1, RB1, H1-0 | KDM4E 992/4885MEN1 576/4885ALDH1A1 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.