SCHEMBL12424737

SCHEMBL12424737

CCc1ccc(C2=C3C(=O)NC(c4ccc(CC)cc4)=C3C(=O)N2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.48
IGF1R P08069 1/20 0.42
PIM1 P11309 1/20 0.42
PIM2 Q9P1W9 1/20 0.42
NOTUM Q6P988 1/20 0.42
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MYC P01106 1/20 0.38
MAX P61244 1/20 0.38
CTSV O60911 1/20 0.38
CTSL P07711 1/20 0.38
TP53 P04637 1/20 0.38
METAP2 P50579 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
MGLL Q99685 2/20 0.37
NISCH Q9Y2I1 1/20 0.37
ALDH1A1 P00352 1/20 0.36
UCHL1 P09936 1/20 0.36
CA12 O43570 1/20 0.36
ALPL P05186 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22431171 0.93 EGFR (0.43) EGFRIGF1RPIM1PIM2NOTUM
SCHEMBL12424770 0.93 PTGS2 (0.44) EGFRIGF1RPIM1PIM2NOTUM
SCHEMBL12424857 0.91 LMNA (0.44) EGFRIGF1RPIM1PIM2NOTUM
SCHEMBL12425027 0.87 EGFR (0.39) EGFRIGF1RPIM1PIM2NOTUM
SCHEMBL12425017 0.84 FYN (0.40) EGFRNOTUMCTSVCTSLTP53
SCHEMBL13917471 0.82 RARB (0.47) NPC1RAB9ACTSVCTSLTP53
SCHEMBL24941273 0.80 HRH3 (0.58)
SCHEMBL12509641 0.80 PTGS2 (0.33)
SCHEMBL12424833 0.79 RARB (0.50) EGFRRAB9ACTSVCTSLTP53
SCHEMBL12509637 0.78 EGFR (0.33) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12019371-B2 Photosensitive composition, film, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2024-06-25 US disclosed
US-11912808-B2 Curable composition, cured product, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2024-02-27 US disclosed
US-11746239-B2 Coloring composition, film, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2023-09-05 US disclosed
US-20220413384-A1 PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-12-29 US disclosed
US-20210155803-A1 COLORING COMPOSITION, CURED FILM, METHOD FOR FORMING PATTERN, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-05-27 US disclosed
WO-2020184244-A1 COLORING COMPOSITION, CURED FILM, PATTERN FORMING METHOD, COLOR FILTER, SOLID-STATE IMAGE SENSOR, AND IMAGE DISPLAY APPARATUS 富士フイルム株式会社 2020-09-17 WO disclosed
WO-2020040043-A1 COLORING COMPOSITION, CURED FILM, PATTERN FORMATION METHOD, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-02-27 WO disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed